2,4-D Chlorocrotyl ester

  • Acetic acid, (2,4-dichlorophenoxy)-4-chloro-2-butenyl ester
  • Crotiline
  • Krotilin
Formula
C12H11Cl3O3
Structure
Uses
Pesticide.

Registry Numbers and Inventories.
CAS
2971-38-2
RTECS
AG8200000
RTECS class
Agricultural Chemical and Pesticide
UN (DOT)
2765
Beilstein/Gmelin
NA
RCRA
U240

Properties.
Formula
C12H11Cl3O3
Formula mass
309.58
Vapor pressure, mmHg
1.5X10-4 @ 25 C
Solubility in water
Insoluble

Hazards and Protection.
Storage
Store at ambient temperatures with open venting.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate clothing to prevent any reasonable probability of skin contact. Wear eye protection to prevent any possibility of eye contact.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
Shelf life of ester formulations varies, depending on the emulsifying system. Some retain satisfactory emulsifying properties after 3 yr.

Fire.
Fire fighting
U.S. Coast guard recommendations-extinguish with dry chemicals, foam, or carbon dioxide. Water may be ineffective. Use water to cool exposed containers. (Cghcd* 78/uscg) DOT recommendations (same as for 2,4-d acid)-small fires: dry chemical, carbon dioxide, waterspray, or foam. Large fires: water spray, fog, or foam. Fight fire from maximum distance. If you can do so without risk, move container from fire area. bureau of explosives recommendations-use extinguishing agent suitable for type of surrounding fire.).
Fire potential
May burn but does not readily ignite. Combustible.
Hazards
Containers may explode when heated.
Combustion products
Irritating hydrogen chloride may form in fire.

Health.
Exposure effects
Low dose exposures - vertigo, headache, malaise, and paresthesias may occur depending on the specific compound involved. High dose exposures - muscle twitching, spasms, profound weakness, polyneuritis, and unconsciousness may occur depending on the specific compound involved. Idiosyncratic reactions - peripheral neuropathies 2,4-D and 2,4,5-T have caused adverse reproductive effects in experimental animals. Allegations of human birth defects due to these compounds have not been confirmed.
   Ingestion
Nausea, vomiting, and diarrhea have been reported. Necrosis of the gastrointestinal mucosa has been reported.
   Inhalation
Ingestion of large amounts may cause bradypnea, respiratory failure, hyperventilation, or pulmonary edema.
   Skin
Direct contact may cause skin irritation. Chlorodioxin contamination of products may produce chloracne with heavy exposure.
   Eyes
See Skin.

First aid
 
   Ingestion
Seek medical assistance.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and jewelry. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing. Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
2765
Response guide
Hazard class
3.2