2,4-Dinitrophenol

  • 1-Hydroxy-2,4-dinitrobenzene
Formula
C6H4N2O5
Structure
Description
Solid yellow crystals.

Registry Numbers and Inventories.
CAS
51-28-5
EC (EINECS/ELINCS)
200-087-7
EC Index Number
609-041-00-4
EC Class
Toxic; Danger of cumulative effects; Dangerous for the Environment
R 23/24/25 33 50
S 28 37 45 61
RTECS
SL2800000
RTECS class
Agricultural Chemical and Pesticide; Drug; Mutagen; Reproductive Effector; Human Data; Primary Irritant
UN (DOT)
1320
Merck
13,3309
Beilstein/Gmelin
1246142
Beilstein Reference
4-06-00-01389
RCRA
P048
EPA OPP
37509
Swiss Giftliste 1
G-1945
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H4N2O5
Formula mass
184.11
Melting point, °C
132 - 133
Boiling point, °C
351
Vapor pressure, mmHg
2E-5 (25 C)
Density
1.675 g/cm3
Solubility in water
1.4 g/L
Surface tension
45.4 g/s2 (91 C)
pKa/pKb
4.41 (pKa)
Partition coefficient, pKow
1.67
Heat of vaporization
61.9 kJ/mol
Heat of combustion
-2710 kJ/mol

Hazards and Protection.
Storage
Dinitrophenol. Should be stored in a cool ventilated place away from area of acute fire hazard and away from powerful oxidizing agents.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Butyl rubber gloves; goggles; impervious lab coat; protective shoes. People exposed to the solid or to a strong soln should wear protective clothing, hand protection and, in confined spaces, the use of respiratory protective equipment.
Respirators
Self-contained breathing apparatus.
Small spills/leaks
Keep sparks, flames, and other sources of ignition away. Keep material wet. Wet spilled material before picking it up. Do not attempt to sweep up dry material.
Stability
Moderate when exposed to heat reactive at high temperature or pressure.
Incompatibilities
Incompatible with heavy metals and their compounds Incompatible with strong oxidizing agents, strong bases and reducing agents Reacts with combustibles.
Decomposition
When heated to decomposition it emits toxic fumes of oxides of nitrogen. Prolonged exposure to fire or heat may result in the spontaneous decomposition and heating with a resultant explosion.

Fire.
Flash Point,°C
135
Fire fighting
Dangerously explosive. Do not fight fires in a cargo of explosives. Evacuate area and let burn.
Fire potential
This material is combustible.
Hazards
May explode if subjected to heat or flame. POISONOUS GAS IS PRODUCED WHEN HEATED. Vapors are toxic. Can detonate or explode when heated under confinement.
Combustion products
Poisonous gas oxides of nitrogen may be produced when heated.

Health.
Poison_Class
2
Exposure effects
Blood pressure, pulse, respiratory rate, and temperature may all be elevated after exposure. In severe poisoning, restlessness, seizures, and coma may occur. Animal studies show developmental malformations involving the neurologic, ophthalmic, urologic, and skeletal systems of offsprings.
   Ingestion
Nausea, vomiting, and abdominal pain may be prominent.
   Inhalation
Dyspnea, tachypnea, cyanosis, and pulmonary edema may occur.
   Skin
Yellow staining of skin occurs following contact with nitrophenols. Diaphoresis is common.
   Eyes
Cataracts, secondary glaucoma, symblepharon, paresis of accomodation, and nystagmus have been reported.

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. Phenols are very toxic poisons AND corrosive and irritating, so that inducing vomiting may make medical problems worse. IMMEDIATELY call a hospital or poison control center and locate activated charcoal, egg whites, or milk in case the medical advisor recommends administering one of them. If advice from a physician is not readily available and the victim is conscious and not convulsing, give the victim a glass of activated charcoal slurry in water or, if this is not available, a glass of milk, or beaten egg whites and IMMEDIATELY transport victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, assure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
1320
Response guide
Hazard class
4.1
Packing Group
I
 
USCG CHRIS Code
DNP
 
Std. Transport #
4901538