2,4,5-Trichlorophenoxyacetic acid

  • 2,4,5-T
  • Trioxone
Formula
C8H5Cl3O3
Structure
Description
White solid. Odorless.
Uses
Herbicide for industrial sites, lumber yards & vacant lots, rangeland & rice, lawns & turf (incl its esters & salts), aquatic use (incl its esters & salts), home use (former use for granules), recreation areas (former use for granules), food crops for humans (former use).

Registry Numbers and Inventories.
CAS
93-76-5
EC (EINECS/ELINCS)
202-273-3
EC Index Number
607-041-00-9
EC Class
Harmful; Irritant; Dangerous for the Environment
RTECS
AJ8400000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector
UN (DOT)
2765
Merck
12,9194
Beilstein/Gmelin
2055620
Beilstein Reference
4-06-00-00973
RCRA
U232
EPA OPP
82001
Swiss Giftliste 1
G-2897
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C8H5Cl3O3
Formula mass
255.48
Melting point, °C
158
Boiling point, °C
376
Vapor pressure, mmHg
2E-6 (25 C)
Vapor density (air=1)
1.8
Odor Threshold Odor threshold Odorless
Density
1.803 g/cm3 (20 C)
Solubility in water
Insoluble
pKa/pKb
2.88 (pKa)
Partition coefficient, pKow
3.23
Heat of vaporization
65.8 kJ/mol
Heat of combustion
-3819 kJ/mol

Hazards and Protection.
Storage
Keep in well ventilated area.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate chemical protective gloves, boots and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
Stable @ its melting-point shelf life excellent depending upon mfr and formulation; 2-yr minimum conditions leading to inStability: Temperatures above 158 C may cause sealed metal containers to burst.
Incompatibilities
Reacts with organic and inorganic bases to form water-soluble salts and with alcohols to form esters Incompatible with strong oxidizing agents and strong bases.
Decomposition
Toxic gases and vapors which include: hydrogen chloride and carbon monoxide. When heated to decomposition it emits toxic fumes of hydrogen chloride.

Fire.
Flash Point,°C
181
Fire fighting
Fire Extinguishing Agents: Water, foam, dry chemical, carbon dioxide
Fire potential
Nonflammable in technical form.
Hazards
Containers may explode when heated.
Combustion products
Toxic hydrogen chloride and phosgene gases may be formed.

Health.
Exposure limit(s)
TLV: ppm; 10 mg/m3 (as TWA) (ACGIH 1994-1995). OSHA PEL: TWA 10 mg/m3 NIOSH REL: TWA 10 mg/m3 NIOSH IDLH: 250 mg/m3
Carcinogin
I-2B
Poison_Class
3
Exposure effects
Low dose exposures - vertigo, headache, malaise, and paresthesias may occur depending on the specific compound involved. High dose exposures - muscle twitching, spasms, profound weakness, polyneuritis, and unconsciousness may occur depending on the specific compound involved. Idiosyncratic reactions - peripheral neuropathies 2,4-D and 2,4,5-T have caused adverse reproductive effects in experimental animals. Allegations of human birth defects due to these compounds have not been confirmed.
   Ingestion
Nausea, vomiting, and diarrhea have been reported. Necrosis of the gastrointestinal mucosa has been reported.
   Inhalation
Ingestion of large amounts may cause bradypnea, respiratory failure, hyperventilation, or pulmonary edema.
   Skin
Direct contact may cause skin irritation. Chlorodioxin contamination of products may produce chloracne with heavy exposure.
   Eyes
Eye, nose, and mouth irritation are possible with direct contact.

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
2765
Response guide
Hazard class
6.1
USCG CHRIS Code
TCA