2,4,5,2',4',5'-Hexabromobiphenyl

  • Hexabromobiphenyl
  • 2,2',4,4',5,5'-Hexabromobiphenyl
  • 2,2'4,4',5,5'-Hexabromo-1,1'-Biphenyl
Formula
C12H4Br6
Structure
Description
White solid.
Uses
Formerly a fire retardant for abs plastics, coatings, lacquers & polyurethane foams.

Registry Numbers and Inventories.
CAS
59080-40-9
RTECS
DV5341000
RTECS class
Reproductive Effector
UN (DOT)
2315
Beilstein/Gmelin
1991358

Properties.
Formula
C12H4Br6
Formula mass
627.62
Melting point, °C
72
Boiling point, °C
455
Solubility in water
insoluble
Partition coefficient, pKow
8.68

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent dust cloud. Avoid inhalation of asbestos dust.
Stability
Degrades readily in UV light.

Fire.
Fire fighting
Small Fires: Dry chemical, carbon dioxide, water spray or regular foam. Large Fires: Water spray, fog or regular foam.
Fire potential
May burn but does not ignite readily.
Hazards
Containers may explode when heated.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Weakness and numbness of the extremities and headache have been reported. Neurobehavioral and psychomotor impairment have been reported after occupational and in utero exposure. One of the potential symptoms of occupational PCB overexposure is decreased birth weight in offspring of exposed mothers. <br>Although relative small quantities of PCBs reach the fetus, significant PCB overexposure can cause teratogenic effects. PBBs are experimental teratogens. <br>Both PCBs and PBBs concentrate in milk.
   Ingestion
Gi upset and diarrhea have been reported.
   Inhalation
Inhalation of material may be harmful.
   Skin
Chloracne is a specific skin reaction associated with cyclic halogenated compounds. Children with in utero high exposures appear to have a higher rate of dermal reactions, including hyperpigmentation, acne and itching.
   Eyes
See Skin.

First aid
 
   Ingestion
Emesis - in almost all cases, ingestions of pcbs or pbbs will not be recognized until long after emesis would be of any value. Vomiting of the pure substance may cause aspiration. Activated charcoal - the value of administering activated charcoal for an acute, known ingestion is unknown. Activated charcoal is a fairly benign treatment, and therefore, should be considered after acute ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. There is little specific treatment. Patients should be monitored for increased hepatic enzymes, chloracne, and the nonspecific eye, gastrointestinal, and neurologic symptoms seen in the yusho poisonings.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
A post-contamination washing cannot be assumed to remove pcbs. In animal studies only 59 percent of applied pcbs were removed from the skin with immediate washings with water and acetone, and only 1 percent was removed washing 24 hours after exposure. Multiple soap and water washings are necessary.
   Eyes
Immediately flush with running water for at least 20 minutes.

Transport.
UN number
2315
Response guide
Hazard class
9
Packing Group
II
 
36. Halogenated hydrocarbons