2,5-Dinitrophenol

  • 2,5-DNP
  • Phenol, gamma-dinitro
  • Phenol, 2,5-dinitro
Formula
C6H4N2O5
Structure
Description
Yellow crystalline solid with a sweet musty odor.
Uses
In manufacture of dyes and organic chemicals, as an indicator.

Registry Numbers and Inventories.
CAS
329-71-5
EC (EINECS/ELINCS)
206-348-1
EC Index Number
609-054-00-5
EC Class
Toxic; Danger of cumulative effects; Dangerous for the Environment
RTECS
SL2900000
RTECS class
Mutagen
UN (DOT)
1663
Merck
12,3334
Beilstein/Gmelin
1913411
Beilstein Reference
4-06-00-01383
Swiss Giftliste 1
G-1946
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C6H4N2O5
Formula mass
184.10
Melting point, °C
108
Boiling point, °C
310
Vapor pressure, mmHg
0.0003 (25 C)
Vapor density (air=1)
6.35
Odor Threshold Odor threshold 2.4 mg/L
Density
1.68 g/cm3 (20 C)
Solubility in water
0.68 g/L
pKa/pKb
5.21 (pKa)
Partition coefficient, pKow
1.75
Heat of vaporization
57.2 kJ/mol
Heat of combustion
-2596 kJ/mol

Hazards and Protection.
Storage
Dinitrophenol. Should be stored in a cool ventilated place away from area of acute fire hazard and away from powerful oxidizing agents. Dinitrophenol
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
People exposed to the solid, or to a strong soln should wear protective clothing, hand protection, and, in confined spaces, the use of respiratory protective equipment.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
ELIMINATE all ignition sources. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
Dried-out material may explode if exposed to heat, flame, or shock.
Incompatibilities
Reacts as weak organic acids Incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides.

Fire.
Flash Point,°C
142
Fire fighting
Fire Extinguishing Agents: Water, dry chemical, CO 2 , foam.
Fire potential
Flammable .
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Vapors are toxic.

Health.
Poison_Class
2
Exposure effects
Blood pressure, pulse, respiratory rate, and temperature may all be elevated after exposure. In severe poisoning, restlessness, seizures, and coma may occur. Animal studies show developmental malformations involving the neurologic, ophthalmic, urologic, and skeletal systems of offsprings.
   Ingestion
Nausea, vomiting, and abdominal pain may be prominent.
   Inhalation
Dyspnea, tachypnea, cyanosis, and pulmonary edema may occur.
   Skin
Yellow staining of skin occurs following contact with nitrophenols. Diaphoresis is common.
   Eyes
Cataracts, secondary glaucoma, symblepharon, paresis of accomodation, and nystagmus have been reported.

First aid
 
   Ingestion
Seek medical assistance.
   Inhalation
Remove from contaminated area. Administer oxygen and artificial respiration as needed.
   Skin
Wash with soap and water.
   Eyes
Flush with water.

Transport.
UN number
1663
Response guide
Hazard class
6.1
Packing Group
III
 
USCG CHRIS Code
DNE