2,5-Piperazinedione

  • 2,5-Diketopiperazine
  • Glycylglycine lactam
  • Diketopiperazine
  • Diglycolyl diamide
  • a,g-Diacipiperazine
  • Cyclo(glycylglycyl)
Formula
C4H6N2O2
Structure
Description
Slightly yellow solid.

Registry Numbers and Inventories.
CAS
106-57-0
EC (EINECS/ELINCS)
203-411-5
S 22 24/25
RTECS
TL6325250
RTECS class
Drug
Merck
12,7619
Beilstein/Gmelin
112112
Beilstein Reference
5-24-05-00294
Canada DSL/NDSL
NDSL
US TSCA
Listed
New Zealand
Listed

Properties.
Formula
C4H6N2O2
Formula mass
114.10
Melting point, °C
92
Boiling point, °C
346
Decomposition point, °C
275
Vapor pressure, mmHg
4E-13 (25 C)
Density
1.593 g/cm3
Solubility in water
Very soluble
pKa/pKb
12.88 (pKa)
Partition coefficient, pKow
-3.81

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with skin and eyes. Avoid ingestion and inhalation. Use with adequate ventilation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.
Disposal code
3
Stability
No data.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Health.
Exposure effects
   Ingestion
The toxicological properties of this substance have not been fully investigated.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
HS Code
2933 59 95