2,5-Xylidine

  • 2,5-Dimethylaniline
  • 2,5-Dimethylbenzenamine
Formula
2,5-(CH3)2C6H3NH2
Structure
Description
Pale yellow to brown liquid.
Uses
Chemical intermediate for solvent red 26, direct violet 7.

Registry Numbers and Inventories.
CAS
95-78-3
EC (EINECS/ELINCS)
202-451-0
EC Index Number
612-027-00-0
EC Class
toxic, dangerous for the environment
R 23/24/25 33 51/53
S 28 36/37 45 61
RTECS
ZE9100000
RTECS class
Tumorigen; Mutagen
UN (DOT)
1711
Merck
12,10217
Beilstein/Gmelin
2205178
Beilstein Reference
4-12-00-02567
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C8H11N
Formula mass
121.18
Melting point, °C
15
Boiling point, °C
218
Vapor pressure, mmHg
0.2 (20 C)
Vapor density (air=1)
4.18
Saturation Concentration
2.0 x 10(5) ppm (20%) at 20 C (calculated)
Odor Threshold Odor threshold 0.0240 mg/m3e
Critical temperature
452
Critical pressure
37.3
Density
0.9790 g/cm3 (20 C)
Solubility in water
Slightly soluble
Refractive index
1.5591 (21 C)
pKa/pKb
9.47 (pKb)
Partition coefficient, pKow
1.83 at pH 7.4
Heat of vaporization
62.8 kJ/mol
Heat of combustion
-4681 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation.
Disposal code
9
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, acids, acid chlorides, halogens, acid anhydrides, hypochlorite, chloroformates.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
97
Autoignition, °C
520
Lower exp. limit, %
1
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water fog, dry chemical, carbon dioxide, or regular foam. Do NOT get water inside containers.
Fire potential
This chemical is combustible.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure limit(s)
NIOSH: Potential Occupational Carcinogen.
Poison_Class
3 (Strong toxins)
Exposure effects
Effects may be delayed.
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause methemoglobinemia, cyanosis, convulsions, and death. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. May be harmful if swallowed.
   Inhalation
May cause respiratory tract irritation. May cause methemoglobinemia, cyanosis, convulsions, tachycardia, dyspnea, and death. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown blood.
   Skin
May cause skin irritation. May be absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1711
Response guide
Hazard class
6.1
Packing Group
II
 
9. Aromatic amines
HS Code
2921 49 10