2,6-Diaminotoluene

  • 1,3-Diamino-2-methylbenzene
  • 2-Methyl-m-phenylenediamine
  • 2-Methyl-1,3-benzenediamine
Formula
C7H10N2
Structure
Description
Prisms from benzene or water.
Uses
Chemical intermediate for toluene diisocyanate, polyether polyols, rubber chemicals, curing agent for epoxy resins, monomer, chain extender & crosslinker for polymers (mixt with 2,4-isomer), chemical intermediate for dyes.

Registry Numbers and Inventories.
CAS
823-40-5
EC (EINECS/ELINCS)
212-513-9
EC Index Number
612-151-00-5
EC Class
Mutagenic Category 3; Harmful; Sensitising; Dangerous for the Environment
R 21/22 43 51/53 68
S 24 36/37 61
RTECS
XS9750000
RTECS class
Mutagen
UN (DOT)
2811
Beilstein/Gmelin
2079476
Beilstein Reference
3-13-00-00291
RCRA
U221
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H10N2
Formula mass
122.19
Melting point, °C
113
Boiling point, °C
280 - 282
Vapor pressure, mmHg
0.003 (25 C)
Critical temperature
512
Critical pressure
45.4
Solubility in water
Very soluble
pKa/pKb
9.26 (pKb)
Partition coefficient, pKow
-0.36
Heat of vaporization
52.3 kJ/mol

Hazards and Protection.
Storage
Storage location should be close to laboratory where it is to be used, so that only small amounts need to be transported. Carcinogens should be kept in only one section of storage area, explosion-proof refrigerator or freezer as required. The area should be appropriately labeled. An inventory should be kept showing the quantity of carcinogen and date it was acquired. Facilities for dispensing should be contiguous to storage area.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Eyes: Wear safety glasses and chemical goggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks
Sweep up, then place into a suitable container for disposal.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents - strong acids.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
148
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential
This material is probably combustible.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure limit(s)
NIOSH: Potential Occupation al Carcinogen.
Exposure effects
CNS effects include headache, dizziness, altered mental status, confusion (lethargy progressing coma), seizures, syncope; occur secondary to CNS hypoxia, usually with levels > 20%.
   Ingestion
Nausea and vomiting may occur.
   Inhalation
Dyspnea and tachypnea may occur.
   Skin
Central cyanosis unresponsive to oxygen therapy is classic.
   Eyes
Redness, pain.

First aid
 
   Ingestion
Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
9. Aromatic amines