2,6-Xylenol

  • 2,6-Dimethylphenol
Formula
(CH3)2C6H3OH
Structure
Description
Colorless to off-white crystalline solid with a sweet tarry odor.
Uses
Intermediate for the manufacture of polyphenylene oxide and modified phenolic resins and phosphate esters used in the production of hydraulic fluids, in halogenation and aminolysis reactions.

Registry Numbers and Inventories.
CAS
576-26-1
EC (EINECS/ELINCS)
209-400-1
EC Index Number
604-006-00-X
EC Class
Toxic; Corrosive; Dangerous for the Environment
R 24/25 34 51/53
S 26 36/37/39 45 61
RTECS
ZE6125000
RTECS class
Tumorigen; Drug; Primary Irritant
UN (DOT)
2261
Merck
12,10215
Beilstein/Gmelin
1446677
Beilstein Reference
4-06-00-03112
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H10O
Formula mass
122.17
Melting point, °C
41 - 42
Boiling point, °C
203
Vapor pressure, mmHg
0.22 (25 C)
Odor Threshold Odor threshold 0.0002 mg/m3
Critical temperature
433
Critical pressure
42.7
Density
1.13 g/cm3 (20 C)
Solubility in water
10 g/L
Surface tension
30 g/s2
Refractive index
1.5148 (65 C)
pKa/pKb
10.66 (pKa)
Partition coefficient, pKow
2.36
Heat of vaporization
45.5 kJ/mol
Heat of combustion
-3260 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.
Disposal code
9
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Bases - acid chlorides - acid anhydrides - oxidizing agents - corrodes steel - brass - copper - copper alloys.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
73
Autoignition, °C
555
Upper exp. limit, %
6.4
Lower exp. limit, %
1.4
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Dust can be an explosion hazard when exposed to heat or flame. Containers may explode when heated. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam. Use agent most appropriate to extinguish fire. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
This chemical is combustible.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects
Chronic ingestion may cause effects similar to those of acute ingestion. May cause kidney damage.
   Ingestion
Harmful if swallowed. May cause irritation of the digestive tract. May cause kidney damage. A case of fatal xylenol ingestion by a long stay mental hospital patient is described. Clinical course was similar to that observed in other phenolic poisonings with active bowel sounds, nausea, and vomiting. Severe metabolic acidosis, hypotension, and cardiac and renal failure.
   Inhalation
May cause respiratory tract irritation.
   Skin
Causes skin irritation. Harmful if absorbed through the skin. May cause skin burns.
   Eyes
Causes eye irritation. May cause eye burns.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Do NOT allow victim to rub or keep eyes closed.

Transport.
UN number
2261
Response guide
Hazard class
6.1
Packing Group
II
 
USCG CHRIS Code
XYL
 
20. Alcohols. Glycols
HS Code
2907 14 00
 
IMO Pollution Category
B