270

  • 3-Methylbut-3-en-2-one
  • Propen-2-yl methyl ketone
  • 3-Methylene-2-butanone
  • 2-Methyl-1-buten-3-one
Formula
C5H8O
Structure
Description
A clear colorless liquid.
Uses
Manufacture of plastics.

Registry Numbers and Inventories.
CAS
814-78-8
EC (EINECS/ELINCS)
212-405-1
RTECS
EN0175000
RTECS class
Primary Irritant
UN (DOT)
1246
Beilstein/Gmelin
1071241
Beilstein Reference
4-01-00-03462
Swiss Giftliste 1
G-2438
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C5H8O
Formula mass
84.13
Melting point, °C
-53.6
Boiling point, °C
60 - 65
Vapor pressure, mmHg
42
Vapor density (air=1)
2.9
Odor Threshold Odor threshold 0.291 ppm
Critical temperature
270
Critical pressure
39.5
Density
0.862 g/cm3 (15 C)
Solubility in water
Soluble
Refractive index
1.4201 (20.1 C)

Hazards and Protection.
Storage
Materials which are toxic as stored or which can decompose into toxic components.Should be stored in a cool, well ventilated place, out of the direct rays of the sun, away from areas of high fire hazard, and should be periodically inspected. Incompatible materials should be isolated. Store at subzero temperature to prevent polymerization.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Protective equipment, including occlusive eye protection to prevent eye damage by vapors should be.Used. Rubber gloves inhibited
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors.
Stability
Polymerizes easily.
Incompatibilities
Oxidizing agents.
Decomposition
Oxides of carbon.

Fire.
Flash Point,°C
21
Upper exp. limit, %
9
Lower exp. limit, %
1.8
Fire fighting
Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use foam, dry chemical, or carbon dioxide.
Fire potential
Flammable, dangerous fire risk
Hazards
May polymerize and explode.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
4
 
Flammability
3
 
 
Reactivity
1
 

Health.
Poison_Class
3
Exposure effects
Limited studies have generally documented little or no effect of ketones on reproduction in experimental animals. Human data is lacking. 2,5-Hexanedione has an effect on spermatogenesis in male experimental animals.
   Ingestion
Nausea and vomiting may occur.
   Inhalation
Ingestion of significant amounts may cause respiratory depression. Pulmonary aspiration may result in chemical pneumonitis.
   Skin
Skin exposure to the liquid or vapor may result in dermatitis and paresthesias of affected areas. Contact urticaria has also been reported.
   Eyes
Splash contact causes irritation, which may be slight, moderate, or severe, depending on the specific ketone; vapors may cause irritation and tearing. Splash contact causes irritation, which may be slight, moderate, or severe, depending on the ketone. Vapors can cause irritation and tearing.

First aid
 
   Ingestion
With ingestion of small amounts the major concern is pulmonary aspiration and gastrointestinal decontamination is not recommended. With ingestion of large amounts there is potential for systemic toxicity from gastrointestinal absorption and gi decontamination is suggested, keeping in mind that pulmonary aspiration is still a concern. If the patient is obtunded, seizing, or has significant alterations in mental status, a cuffed endotracheal tube should be inserted prior to gastric aspiration. For moderate ingestions (less than 100 milliliters) activated charcoal alone is recommended.
   Inhalation
Remove victim from exposure; give artificial respiration if needed; call physician.
   Skin
Wash off skin with large volumes of water for 15 min.; call physician if burn has occurred.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
1246
Response guide
Hazard class
3
Packing Group
II
 
USCG CHRIS Code
MPK
 
Std. Transport #
4907240