- Propen-2-yl methyl ketone
A clear colorless liquid.
Manufacture of plastics.
Registry Numbers and Inventories.
Swiss Giftliste 1
Japan ENCS (MITI)
Melting point, °C
Boiling point, °C
60 - 65
Vapor pressure, mmHg
Vapor density (air=1)
Odor Threshold Odor threshold 0.291 ppm
0.862 g/cm3 (15 C)
Solubility in water
1.4201 (20.1 C)
Hazards and Protection.
Materials which are toxic as stored or which can decompose into toxic components.Should be stored in a cool, well ventilated place, out of the direct rays of the sun, away from areas of high fire hazard, and should be periodically inspected. Incompatible materials should be isolated. Store at subzero temperature to prevent polymerization.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protective equipment, including occlusive eye protection to prevent eye damage by vapors should be.Used. Rubber gloves inhibited
Wear positive pressure self-contained breathing apparatus (SCBA).
Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors.
Oxides of carbon.
Upper exp. limit, %
Lower exp. limit, %
Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use foam, dry chemical, or carbon dioxide.
Flammable, dangerous fire risk
May polymerize and explode.
Fire may produce irritating, corrosive and/or toxic gases.
Limited studies have generally documented little or no effect of ketones on reproduction in experimental animals. Human data is lacking. 2,5-Hexanedione has an effect on spermatogenesis in male experimental animals.
Nausea and vomiting may occur.
Ingestion of significant amounts may cause respiratory depression. Pulmonary aspiration may result in chemical pneumonitis.
Skin exposure to the liquid or vapor may result in dermatitis and paresthesias of affected areas. Contact urticaria has also been reported.
Splash contact causes irritation, which may be slight, moderate, or severe, depending on the specific ketone; vapors may cause irritation and tearing. Splash contact causes irritation, which may be slight, moderate, or severe, depending on the ketone. Vapors can cause irritation and tearing.
With ingestion of small amounts the major concern is pulmonary aspiration and gastrointestinal decontamination is not recommended. With ingestion of large amounts there is potential for systemic toxicity from gastrointestinal absorption and gi decontamination is suggested, keeping in mind that pulmonary aspiration is still a concern. If the patient is obtunded, seizing, or has significant alterations in mental status, a cuffed endotracheal tube should be inserted prior to gastric aspiration. For moderate ingestions (less than 100 milliliters) activated charcoal alone is recommended.
Remove victim from exposure; give artificial respiration if needed; call physician.
Wash off skin with large volumes of water for 15 min.; call physician if burn has occurred.
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.
USCG CHRIS Code
Std. Transport #