3-Bromophenyl isocyanate

  • m-Bromophenyl isocyanate
  • 1-Isocyanato-3-bromobenzene
  • Benzene, 1-bromo-3-isocyanato-
  • Isocyanic acid, m-bromophenyl ester
Formula
C7H4BrNO
Structure
Description
Colorless liquid.

Registry Numbers and Inventories.
CAS
23138-55-8
R 23/25 36/37/38 42
S 23 26 36/37/39 45
UN (DOT)
2206
Beilstein/Gmelin
2802537
Beilstein Reference
3-12-00-01427

Properties.
Formula
C7H4BrNO
Formula mass
198.01
Boiling point, °C
220
Vapor density (air=1)
6.83
Density
1.586 g/cm3
Solubility in water
Insoluble
Refractive index
1.59 (20 C)

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). Storage under a nitrogen blanket has been recommended. Store protected from moisture.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Do not allow contact with water. Wash clothing before reuse. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation. Do not get water inside containers.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Oxidizing agents.
Decomposition
Carbon monoxide, oxides of nitrogen, irritating and toxic fumes and gases, carbon dioxide, bromine fumes.

Fire.
Flash Point,°C
108
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode when heated. Extinguishing media: Use agent most appropriate to extinguish fire. Do NOT get water inside containers. Cool containers with flooding quantities of water until well after fire is out. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Hazards
Vapors form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects
Repeated or prolonged exposure may cause allergic reactions in sensitive individuals.
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
   Inhalation
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. In rare instances, exposure may cause sensitization, resulting in inflammation of the mucous membranes and in eczematous eruptions.
   Skin
Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
   Eyes
Causes eye irritation. Lachrymator.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Do NOT allow victim to rub or keep eyes closed.

Transport.
UN number
2206
Response guide
Hazard class
6.1
Packing Group
II; III