3-Chloro-1-propanol

  • 1-Chloro-3-hydroxypropane
  • Trimethylene chlorohydrin
  • 3-Chloropropan-1-ol
  • 3-Chloropropanol-1
Formula
Cl(CH2)3OH
Structure
Description
A colorless liquid with a mild odor.
Uses
Used to make plastics, resins and other chemicals.

Registry Numbers and Inventories.
CAS
627-30-5
EC (EINECS/ELINCS)
210-992-9
EC Class
harmful, irritant
R 22 36/37/38
S 23 36/37
RTECS
UA8930000
RTECS class
Mutagen
UN (DOT)
2849
Beilstein/Gmelin
773655
Beilstein Reference
4-01-00-01441
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H7ClO
Formula mass
94.54
Melting point, °C
-20
Boiling point, °C
161
Vapor pressure, mmHg
1.1 (25 C)
Vapor density (air=1)
3.26
Critical temperature
334
Critical pressure
46.9
Density
1.1309 g/cm3 (20 C)
Solubility in water
300 g/L
Viscosity
6 mPa 20.00 C
Refractive index
1.44458 (20 C)
Partition coefficient, pKow
0.54

Hazards and Protection.
Storage
Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C).
Handling
Wash thoroughly after handling. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Disposal code
2
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Oxidizing agents
Decomposition
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
73
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Runoff from fire control or dilution water may cause pollution. Extinguishing media: Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
May burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. May polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
2
 
 
Reactivity
0
 

Health.
Exposure effects
May cause liver and kidney damage. Effects may be delayed.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May cause cardiac disturbances. May cause central nervous system depression.
   Inhalation
Causes respiratory tract irritation. May cause liver and kidney damage. Aspiration may lead to pulmonary edema. May cause cardiac abnormalities. Can produce delayed pulmonary edema. Inhalation at high concentrations may cause CNS depression and asphixiation.
   Skin
Causes skin irritation. May cause cyanosis of the extremities.
   Eyes
Causes eye irritation. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2849
Response guide
Hazard class
6.1
Packing Group
III
 
HS Code
2905 59 10
 
Std. Transport #
4925164