3-Chloro-p-toluidine

  • 3-Chloro-4-methylaniline
  • 3-Chloro-4-Methyl-Benzenamine
  • 4-Amino-2-chlorotoluene
  • 2-Chloro-4-aminotoluene
Formula
C7H8ClN
Structure
Description
Brown solid with a mild odor.
Uses
Chemical intermediate for the acid dye palatine fast yellow, bird control agent.

Registry Numbers and Inventories.
CAS
95-74-9
EC (EINECS/ELINCS)
202-446-3
R 20/21/22 36/38 50/53
S 28 36/37/39 61
RTECS
XU5111000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen
UN (DOT)
2239
Beilstein/Gmelin
636511
Beilstein Reference
4-12-00-01985
EPA OPP
128979
Canada DSL/NDSL
DSL
US TSCA
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H8ClN
Formula mass
141.61
Melting point, °C
26
Boiling point, °C
237
Vapor pressure, mmHg
0.085
Vapor density (air=1)
4.9
Density
1.108 g/cm3 (20 C)
Solubility in water
< 1 mg/ml
Refractive index
1.58 (20 C)
Partition coefficient, pKow
2.58

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
100
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
This chemical is combustible.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects
May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis, rapid heart rate, unconsciousness and possible death.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. May be harmful if swallowed. This product contains nitrite which may cause methemoglobinemia
   Inhalation
May cause respiratory tract irritation. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown blood. Inhalation of aniline causes anoxia due to the formation of methemoglobinemia.
   Skin
May cause skin irritation. May be absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2239
Response guide
Hazard class
6.1
Packing Group
III