3-Chloropropanoyl chloride

  • b-Chloropropanoyl chloride
  • 3-Chloropropionyl chloride
Formula
ClCH2CH2COCl
Structure
Description
Clear, brown liquid.

Registry Numbers and Inventories.
CAS
625-36-5
EC (EINECS/ELINCS)
210-890-4
EC Class
flammable, very toxic, corrosive
R 10 14 26 22 35
S 26 28 36/37/39 45
UN (DOT)
2927
Beilstein/Gmelin
635814
Beilstein Reference
4-02-00-00750
Swiss Giftliste 1
G-8689
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H4Cl2O
Formula mass
126.97
Melting point, °C
-32
Boiling point, °C
143
Vapor pressure, mmHg
7.5 (20 C)
Vapor density (air=1)
4.4
Density
1.330 g/cm3 (20 C)
Solubility in water
Decomposes
Viscosity
1.4 mPas
Refractive index
1.4549 (20 C)

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry place. Keep container closed when not in use. Store in a tightly closed container. Keep away from water. Flammables-area.
Handling
Do not allow water to get into the container because of violent reaction. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Use with adequate ventilation. Use only in a chemical fume hood. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Do not expose spill to water. A vapor suppressing foam may be used to reduce vapors.
Disposal code
11
Stability
Combines vigorously or explosively with water.
Incompatibilities
Acids, oxidizing materials, water.
Decomposition
Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
49
Autoignition, °C
490
Upper exp. limit, %
20.2
Lower exp. limit, %
8.8
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Water Reactive. Material will react with water and may release a flammable and/or toxic gas. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. May ignite or explode on contact with steam or moist air. Extinguishing media: Use dry sand or earth to smother fire. Do NOT use water directly on fire. Use water spray to cool fire-exposed containers. Use foam, dry chemical, or carbon dioxide. Do NOT use straight streams of water. Contact professional fire-fighters immediately.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Water Reactive. Material will react with water and may release a flammable and/ortoxic gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
3
 
 
Reactivity
2
 

Health.
Poison_Class
2
Exposure effects
   Ingestion
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns.
   Inhalation
Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. Vapors may cause dizziness or suffocation.
   Skin
Causes severe burns with delayed tissue destruction.
   Eyes
Causes eye burns. Lachrymator.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
2927
Response guide
Hazard class
6.1
Packing Group
I; II
 
HS Code
2915 90 80