3-Mercaptopropyl trimethoxylsilane

  • 3-(Trimethoxysilyl)-1-propanethiol
  • 3-(Trimethoxysilyl)propyl mercaptan
  • 3-(Sulfanylpropyl)trimethoxysilane
  • Silquest A 189
  • Prosil 196
  • Dynasylan NTNS
Formula
(CH3O)3Si(CH2)3SH
Structure
Description
Clear, colorless liquid. With a stench.
Uses
Coupling agent.

Registry Numbers and Inventories.
CAS
4420-74-0
EC (EINECS/ELINCS)
224-588-5
EC Class
harmful, sensitizing, dangerous for the environment
R 22 51/53
S 28 36/37 60 61
RTECS
TZ7800000
RTECS class
Organometallic; Primary Irritant
UN (DOT)
3082
Beilstein/Gmelin
2038119
Swiss Giftliste 1
G-4790
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H16O3SSi
Formula mass
196.34
Melting point, °C
-50
Boiling point, °C
215
Vapor pressure, mmHg
0.52 (25 C)
Vapor density (air=1)
6.77
Density
1.056 g/cm3
Solubility in water
Slightly soluble
Refractive index
1.4441 (20 C)
pKa/pKb
10.55 (pKa)
Partition coefficient, pKow
1.09
Heat of vaporization
41.6 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not allow contact with water. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Use a spark-proof tool. Provide ventilation. Do not get water inside containers.
Disposal code
6
Stability
Stable under normal temperatures and pressures. Moisture sensitive.
Incompatibilities
Strong oxidizing agents, strong acids, alcohols, moisture, water.
Decomposition
Carbon monoxide, oxides of sulfur, carbon dioxide, silicon oxide.

Fire.
Flash Point,°C
49
Autoignition, °C
235
Upper exp. limit, %
44
Lower exp. limit, %
5.5
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Extinguishing media: Use water spray to cool fire-exposed containers. Do NOT get water inside containers. In case of fire, use carbon dioxide, dry chemical powder or appropriate foam.
Health
1
 
Flammability
2
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
Aspiration may lead to pulmonary edema. Inhalation at high concentrations may cause CNS depression and asphixiation.
   Skin
Causes mild skin irritation. May cause dermatitis. May cause cyanosis of the extremities.
   Eyes
May cause eye irritation. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
3082
Response guide
HS Code
2931 00 95