3-Methoxyaniline

  • m-Anisidine
  • 1-Amino-3-methoxybenzene
  • 3-Methoxyphenylamine
Formula
3-(CH3O)C6H4NH2
Structure
Description
Pale yellow oily liquid or dark red liquid.

Registry Numbers and Inventories.
CAS
536-90-3
EC (EINECS/ELINCS)
208-651-4
EC Class
very toxic, dangerous for the environment
R 26/27/28 33
S 28 36/37 45
RTECS
BZ5408000
RTECS class
Mutagen
UN (DOT)
2431
Merck
13,670
Beilstein/Gmelin
386119
Beilstein Reference
4-13-00-00953
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C7H9NO
Formula mass
123.16
Melting point, °C
-2 - 0
Boiling point, °C
251
Vapor pressure, mmHg
0.02 (25 C)
Density
0.997 g/cm3 (13 C)
Solubility in water
Soluble
Surface tension
33 g/s2 (131 C)
Refractive index
1.5809 (20 C)
pKa/pKb
9.83 (pKb)
Partition coefficient, pKow
0.84
Heat of vaporization
48.8 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not get on skin or in eyes. Do not ingest or inhale.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.
Disposal code
1
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
110
Autoignition, °C
545
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential
This chemical is probably combustible.

Health.
Exposure effects
May cause cancer according to animal studies.
   Ingestion
May cause irritation of the digestive tract. May cause kidney damage. May cause methemoglobinemia, cyanosis, convulsions, and death. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood.
   Inhalation
May cause severe allergic respiratory reaction. May cause respiratory tract irritation.
   Skin
May be absorbed through the skin in harmful amounts. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. If absorbed, may cause symptoms similar to those for ingestion.
   Eyes
Causes severe eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if symptoms occur.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2431
Response guide
HS Code
2922 22 00