3-Nitropropionic acid

  • BNP
  • Bovinocidin
  • Hiptagenic acid
  • 3-Nitropropanoic acid
  • beta-Nitropropionic acid
Formula
C3H5NO4
Structure
Description
Golden crystals (from chloroform).
Uses
Research chemical.

Registry Numbers and Inventories.
CAS
504-88-1
EC (EINECS/ELINCS)
208-003-0
RTECS
UF6220000
RTECS class
Tumorigen; Mutagen
UN (DOT)
2811
Beilstein/Gmelin
1759889
Beilstein Reference
4-02-00-00771

Properties.
Formula
C3H5NO4
Formula mass
119.07
Melting point, °C
67
Density
1.59 g/cm3
Solubility in water
Very soluble
pKa/pKb
3.66 (pKa)
Partition coefficient, pKow
-0.40

Hazards and Protection.
Storage
Refrigerator (approx 4 C).
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks
Sweep up, then place into a suitable container for disposal.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Bases - oxidizing agents - reducing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
Fire potential
This material is probably combustible.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
CNS effects include headache, dizziness, altered mental status, confusion (lethargy progressing coma), seizures, syncope; occur secondary to CNS hypoxia, usually with levels > 20%.
   Ingestion
Nausea and vomiting may occur.
   Inhalation
Dyspnea and tachypnea may occur.
   Skin
Central cyanosis unresponsive to oxygen therapy is classic.
   Eyes
See Inhalation.

First aid
 
   Ingestion
Do NOT induce vomiting. Allow the victim to rinse his mouth and then to drink 2-4 cupfuls of water, and seek medical advice.
   Inhalation
Remove from exposure to fresh air immediately.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
I; II; III