3-alpha,5-alpha-Tetrahydroprogesterone

  • Allotetrahydroprogesterone
  • 3-alpha-Hydroxy-5-alpha-pregnan-20-one
  • 3-alpha,5-alpha-Pregnanolone
  • Pregnan-20-one, 3-hydroxy-, (3-alpha,5-alpha)- (9CI)
Formula
C21H34O2
Structure
Description
White solid.

Registry Numbers and Inventories.
CAS
516-54-1
RTECS
TU4383000
Merck
12,283
Beilstein/Gmelin
3211363
Beilstein Reference
4-08-00-00664

Properties.
Formula
C21H34O2
Formula mass
318.5
Melting point, °C
176 - 178
Boiling point, °C
431
Vapor pressure, mmHg
3.1E-9 (25 C)
Density
1.053 g/cm3 (20 C)
pKa/pKb
15.11 (pKa)
Partition coefficient, pKow
4.89
Heat of vaporization
79.3 kJ/mol

Hazards and Protection.
Storage
Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 20 C.
Protection
Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.
Small spills/leaks
Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Oxidizing agents.

Fire.
Flash Point,°C
184
Fire fighting
Extinguishing media: SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet. Wear positive pressure self-contained breathing apparatus (SCBA) and full turnout gear.
Fire potential
May be combustible at high temperature.
Health
0
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects

First aid
 
   Ingestion
:Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.
   Inhalation
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
   Skin
In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
   Eyes
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention.

Transport.