3-tert-Butyl-4-hydroxyanisole

  • 3-BHA
  • 2-tert-Butyl-4-methoxyphenol
  • 4-Methoxy-2-tert-butylphenol
  • 2-(1,1-Dimethylethyl)-4-methoxyphenol
Formula
C11H16O2
Structure
Description
Solid.
Uses
Component of bha (a commonly used food additive).

Registry Numbers and Inventories.
CAS
121-00-6
EC (EINECS/ELINCS)
204-442-7
RTECS
SK1575000
RTECS class
Tumorigen; Mutagen
Beilstein/Gmelin
1867499
Beilstein Reference
4-06-00-06013
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C11H16O2
Formula mass
180.25
Melting point, °C
60 - 61
Boiling point, °C
267 - 269
Vapor pressure, mmHg
0.0045 (25 C)
Density
1.0587 g/cm3 (20 C)
Solubility in water
Insoluble
Refractive index
1.5308 (20 C)
pKa/pKb
11.82 (pKa)
Partition coefficient, pKow
3.00
Heat of vaporization
52.8 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
Wash throughly after handling.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
NIOSH approved respirator.
Small spills/leaks
Wear approved protective equipment. Cover with dry lime or soad ash. Pick up and keep in a closed ontainer. Avoid raising dust. Ventilate area. Wash spill site after material pickup is complete.
Stability
Stable.
Incompatibilities
Strong oxidizing agents.
Decomposition
Oxides of carbon.

Fire.
Flash Point,°C
106
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Poison_Class
4 (Substances and products that must be considered harmful)
Exposure effects
Harmful if swallowed, inhaled or absorbed through the skin. Causes irritation. Prolonged exposure or repeated contact may cause allergic reactions in sensitive individuals.

First aid
 
   Ingestion
Following ingestion and/or prior to gastric evacuation, immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 15 ml/kg in a child). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Emesis: ipecac-induced vomiting is not recommended because of the potential for cns depression. Fluid and electrolyte abnormalities should be corrected if noted.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.
HS Code
2909 50 90