3,3'-Biphenyldicarboxylic acid, 4,4'-diamino

  • 3,3'-Benzidinedicarboxylic acid
  • 5,5'-Bianthranilic acid
  • 4,4'-Diamino-3,3'-biphenyldicarboxylic acid
  • 4,4'-Diaminobiphenyl-3,3'-dicarboxylic acid
  • 3,3'-Dicarboxybenzidine
Formula
C14H12N2O4
Structure
Description
White crystals.
Uses
Dyestuff. Used for the manufacture of azo dyes containing copper.

Registry Numbers and Inventories.
CAS
2130-56-5
EC (EINECS/ELINCS)
218-348-9
RTECS
DV3325000
RTECS class
Tumorigen; Mutagen
Beilstein/Gmelin
2815505
Beilstein Reference
2-14-00-00345
Canada DSL/NDSL
NDSL
US TSCA
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C14H12N2O4
Formula mass
272.28
Boiling point, °C
558
Vapor pressure, mmHg
3E-13 (25 C)
Solubility in water
Very soluble
pKa/pKb
4.51 (pKa)
Heat of vaporization
88.3 kJ/mol

Hazards and Protection.
Decomposition
When heated to decomp it emits toxic fumes of nitrogen oxides.

Fire.
Flash Point,°C
291

Health.
Exposure effects
   Ingestion
Nausea and vomiting may occur.
   Inhalation
Dyspnea and tachypnea may occur.. CNS effects include headache, dizziness, altered mental status, confusion, lethargy progressing to coma seizures and syncope; these occur secondary to CNS hypoxia, usually with levels > 20 percent.
   Skin
Central cyanosis unresponsive to oxygen therapy is classic.

First aid
 
   Ingestion
1. Consider gastric lavage after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Protect airway by placement in Trendelenburg and left lateral decubitus position or by endotracheal intubation. Control any seizures first. 2. Administer charcoal as a slurry 240 mL water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents, 25 to 50 g in children (1 to 12 years), and 1 g/kg in infants less than 1 year old. 3. Immediate dilution with milk or water may be of benefit in caustic or irritant chemical ingestions.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. Respiratory tract irritation, if severe, can progress to pulmonary edema which may be delayed in onset up to 24 to 72 hours after exposure in some cases.
   Skin
Skin should be thoroughly washed with soap and water Contaminated clothing and shoes should be discarded Seek medical attention. Administer 100 percent humidified supplemental oxygen with assisted ventilation as required. Treat for methemoglobinemia and sequelae. Signs and symptoms of methemoglobinemia may be delayed.
   Eyes
Irrigate exposed eyes with copious amounts of room temperature water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.