3,3'-Dimethoxybenzidine

  • o-Dianisidine
  • 3,3’-Dimethoxy-[1,1’-biphenyl]-4,4’-diamine
Formula
C14H16N2O2
Structure
Description
Colorless crystals or a light brown powder. Turns violet on standing.
Uses
Chemical intermediate in prodn of o-dianisidine diisocyanate , for detection of presence of thiocyanates, nitrites & a number of metals.

Registry Numbers and Inventories.
CAS
119-90-4
EC (EINECS/ELINCS)
204-355-4
EC Index Number
612-036-00-X
EC Class
Carcinogenic Category 2; Harmful
R 45 22
RTECS
DD0875000
RTECS class
Tumorigen; Mutagen
UN (DOT)
3143
Merck
13,3012
Beilstein/Gmelin
1879884
Beilstein Reference
4-13-00-02834
RCRA
U091
Swiss Giftliste 1
G-1489
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C14H16N2O2
Formula mass
244.29
Melting point, °C
137-138
Boiling point, °C
403
Vapor pressure, mmHg
9E-9
Vapor density (air=1)
8.5
Critical temperature
616
Critical pressure
27.9
Solubility in water
Slightly soluble
Partition coefficient, pKow
1.808

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, oxides of nitrogen, carbon dioxide.

Fire.
Flash Point,°C
206 (closed cup)
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Fire potential
This chemical is combustible.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
1
 
 
Reactivity
0
 

Health.
Carcinogin
I-2B, N-2, CP65
Poison_Class
1*
Exposure effects
May cause cancer according to animal studies.
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.
   Inhalation
Inhalation of dust may cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
Dust may cause mechanical irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
3143
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
USCG CHRIS Code
DTB