- t-Butyl methyl ketone
- tert-Butyl methyl ketone
- Methyl t-butyl ketone
Clear to light yellow liquid, peppermint or camphor-like odor.
Produced in large amounts for fungicides, eg triademefon, an important intermediate for this type of fungicide is triazolylpinacolone, a further use is the synthesis of herbicides, eg metribuzin.
Registry Numbers and Inventories.
highly flammable, harmful
R 11 22
S 16 23 24/25
Japan ENCS (MITI)
Melting point, °C
Boiling point, °C
Vapor pressure, mmHg
Vapor density (air=1)
0.8665 g/cm3 (0 C)
Solubility in water
0.15 cp (0 C)
2.9879e-02 newtons/m @ melting point
1.3995 (18 C)
Heat of vaporization
Heat of combustion
Hazards and Protection.
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Keep containers tightly closed.
Wash thoroughly after handling. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Use with adequate ventilation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Stable under normal temperatures and pressures. Volatile in steam.
Strong oxidizing agents.
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, acrid smoke and fumes.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
Flammable/combustible material. May be ignited by friction, heat, sparks or flames.
Fire may produce irritating and/or toxic gases.
Limited studies have generally documented little or no effect of ketones on reproduction in experimental animals. Human data is lacking. 2,5-Hexanedione has an effect on spermatogenesis in male experimental animals.
May cause irritation of the digestive tract. May be harmful if swallowed.
May cause respiratory tract irritation. Vapors may cause dizziness or suffocation.
May cause skin irritation.
May cause eye irritation.
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.