3,3'-dichlorobenzidine

  • 3,3-Dichloro-(1,1’-biphenyl)-4,4’diamine
  • 4,4'-Diamino-3,3'-dichlorobiphenyl
Formula
C12H10Cl2N2
Structure
Description
Gray to purple crystalline powder.
Uses
Manufacture azo dyes.

Registry Numbers and Inventories.
CAS
91-94-1
EC (EINECS/ELINCS)
202-109-0
EC Index Number
612-068-00-4
EC Class
Carcinogenic Category 2; Harmful; Sensitising; Dangerous for the Environment
RTECS
DD0525000
RTECS class
Tumorigen; Mutagen; Reproductive Effector
UN (DOT)
1885
Merck
12,3109
Beilstein/Gmelin
2108022
Beilstein Reference
4-13-00-00384
RCRA
U073
Swiss Giftliste 1
G-2009
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C12H10Cl2N2
Formula mass
253.13
Melting point, °C
132-133
Boiling point, °C
368
Vapor pressure, mmHg
4E-6 (25 C)
Solubility in water
Insoluble
pKa/pKb
11.30 (pKb)
Partition coefficient, pKow
3.02
Heat of vaporization
63.4 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
You should dampen the solid spill material with acetone, then transfer the dampened material to a suitable container. Use absorbent paper dampened with acetone to pick up any remaining material. Seal your contaminated clothing and the adsorbent paper in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a strong soap and water solution. Do not reenter the contaminate area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
No data.
Incompatibilities
Incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.
Decomposition
When heated to decomposition it emits very high toxic fumes of hydrogen chloride and nitrogen oxides.

Fire.
Flash Point,°C
186
Autoignition, °C
350
Fire fighting
This compound is not very flammable but any fire involving this compound may produce dangerous vapors. You should evacuate the area. All firefighters should wear full-body protective clothing and use self-contained breathing apparatuses. You should extinguish any fires involving this chemical with a dry chemical, carbon dioxide, foam, or halon extinguisher.
Fire potential
This material is combustible.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Elemental chlorine and nitrogen oxide may be liberated upon incineration.

Health.
Exposure limit(s)
TLV: ppm; mg/m3 A2 (skin) (ACGIH 1993-1994).
Carcinogin
O, G-A3, I-2B, N-2, CP65
Poison_Class
1*
Exposure effects
   Ingestion
Nausea, vomiting and diarrhea are possible if ingested.
   Inhalation
Cough, tachypnea, and wheezing are common after inhalation.
   Skin
Redness, swelling and pain may occur.
   Eyes
Irritants may cause swelling, redness and pain at any site, especially at mucous membranes. The mouth, nose, and eyes are susceptible to these effects.

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
1885
Response guide
Hazard class
6.1
Packing Group
II
 
USCG CHRIS Code
DCZ