3,4-Xylylamine

  • 3,4-Dimethylaniline
Formula
3,4-(CH3)2C6H3NH2
Structure
Description
Pale brown crystals or off-white solid.
Uses
Used as a chemical intermediate for the synthesis of riboflavin.

Registry Numbers and Inventories.
CAS
95-64-7
EC (EINECS/ELINCS)
202-437-4
EC Index Number
612-027-00-0
EC Class
toxic, dangerous for the environment
R 23/24/25 33 51/53
S 28 36/37 45 61
RTECS
ZE9450000
RTECS class
Mutagen
UN (DOT)
1711
Merck
12,10217
Beilstein/Gmelin
507414
Beilstein Reference
4-12-00-02502
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C8H11N
Formula mass
121.18
Melting point, °C
48 - 51
Boiling point, °C
226
Odor Threshold Odor threshold 0.0240 mg/m3
Critical temperature
452
Critical pressure
37.3
Density
1.0755 g/cm3 (18 C)
Solubility in water
Slightly soluble
pKa/pKb
8.72 (pKb)
Partition coefficient, pKow
1.84

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid generating dusty conditions.
Disposal code
9
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, acids, acid chlorides, halogens, acid anhydrides, hypochlorite, chloroformates.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
>100
Autoignition, °C
580
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water fog, dry chemical, carbon dioxide, or regular foam. Do NOT get water inside containers.
Fire potential
This chemical is combustible.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure limit(s)
NIOSH: Potential Occupational Carcinogen.
Poison_Class
3 (Strong toxins)
Exposure effects
Effects may be delayed.
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause methemoglobinemia, cyanosis, convulsions, and death. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. May be harmful if swallowed.
   Inhalation
May cause respiratory tract irritation. May cause methemoglobinemia, cyanosis, convulsions, tachycardia, dyspnea, and death. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown blood.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1711
Response guide
Hazard class
6.1
Packing Group
II
 
9. Aromatic amines
HS Code
2921 49 10