3,5-Dinitrotoluene

  • 1-Methyl-3,5-dinitrobenzene
  • 5-Methyl-1,3-dinitrobenzene
  • 3,5-DNT
Formula
C7H6N2O4
Structure
Description
Yellowish, reddish needles from acetic acid.
Uses
Intermediates for production of toluene diisocyanate. Dinitrotoluenes.

Registry Numbers and Inventories.
CAS
618-85-9
EC (EINECS/ELINCS)
210-566-2
EC Index Number
609-052-00-4
EC Class
Carcinogenic Category 2; Mutagenic Category 3; Toxic for reproduction Category 3; Toxic; Harmful; Dangerous for the Environment
RTECS
XT2150000
RTECS class
Tumorigen; Mutagen
UN (DOT)
2038
Beilstein/Gmelin
2052045
Beilstein Reference
4-05-00-00867
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C7H6N2O4
Formula mass
182.15
Melting point, °C
93
Boiling point, °C
315
Vapor pressure, mmHg
0.0013 (25 C)
Density
1.2772 g/cm3 (111 C)
Solubility in water
Insoluble
Partition coefficient, pKow
2.28
Heat of vaporization
52.6 kJ/mol

Hazards and Protection.
Storage
Unspecified dinitrotoluene solid--separate from strong oxidizers and from reducing agents, protect from damage to container. Store in a cool, well-ventilated area away from ignition sources. Stack drums no more than two high and no more than four per pallet. Outdoor storage is preferred.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate personal protective clothing to prevent skin contact. Wear appropriate eye protection to prevent eye contact. Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure.
Respirators
Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive pressure-mode. Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive-pressure mode.
Small spills/leaks
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
Dinitrotoluenes may explode if confined while burning. Dinitrotoluene can be detonated only by a very strong initiator. It may be an explosion hazard when involved in a fire. Moderate explosion hazard. May explode from heat or contamination if confined.
Incompatibilities
Avoid contact with strong oxidizers, caustics, metals such as tin and zinc.

Fire.
Flash Point,°C
152
Upper exp. limit, %
8.2
Lower exp. limit, %
1.5
Fire fighting
DOT recommendations for dinitrotoluenes-small fires: dry chemical, carbon dioxide, water spray, or foam. Large fires: water spray, fog, or foam. Move container from fire area if you can do so without risk. Cool containers that are exposed to flames with water from the side until well after fire is out.
Fire potential
Dinitrotoluenes may burn but do not ignite readily. Combustible: moderate fire hazard.
Hazards
Containers may explode when heated.
Combustion products
When heated to decomposition it emits toxic fumes of nitrogen oxides.

Health.
Exposure limit(s)
IDHL: NIOSH considers dinitrotoluene to be a potential occupational carcinogen.
Exposure effects
Respiratory depression secondary to hypoxia may occur. CNS depression is secondary to hypoxia from methemoglobinemia. DNT was NOT teratogenic in rats, and had no effects in a 3- generation study in rats. Testicular effects have been seen in laboratory animals, but not in exposed workers.
   Ingestion
Nausea and vomiting may be secondary to methemoglobinemia.
   Inhalation
Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Effects of contact or inhalation may be delayed.
   Skin
Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact.
   Eyes
Headache can occur.

First aid
 
   Ingestion
Do not induce vomiting - following ingestion and/or prior to gastric evacuation, immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 15 ml/kg in a child).
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Administer oxygen to all cyanotic patients.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Treatment should include recommendations listed in the oral exposure section when appropriate.

Transport.
UN number
2038
Response guide
Hazard class
6.1
Packing Group
II
 
42. Nitro compounds