3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(2,3-dichlorophenyl)-2,6-dimethyl-, ethyl methyl ester

  • Ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
  • Felodipine
  • H 154/82
  • Modip
  • Plendil
Formula
C18H19Cl2NO4
Structure

Registry Numbers and Inventories.
CAS
72509-76-3
RTECS
US7968700
Merck
12,3991
Beilstein/Gmelin
4331472

Properties.
Formula
C18H19Cl2NO4
Formula mass
384.26
Melting point, °C
145
Boiling point, °C
472
Vapor pressure, mmHg
4.6E-9 (25 C)
Density
1.277 g/cm3 (20 C)
pKa/pKb
11.27 (pKb)
Partition coefficient, pKow
4.83
Heat of vaporization
73.4 kJ/mol

Hazards and Protection.
Storage
Store in original container in a cool dark place.
Protection
Wear self-contained breathing apparatus, rubber boots & heavy rubber gloves.
Small spills/leaks
Sweep-up/absorb in suitable material, place in a container and hold for disposal. Avoid raising dust. Ventilate area and wash spill site after pickup is complete.

Fire.
Flash Point,°C
239
Fire fighting
Extinguish with carbon dioxide, dry chemical powder or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with the skin and eyes.
Combustion products
Emits toxic fumes under fire conditions.

Health.
Exposure effects

First aid
 
   Ingestion
If swallowed, wash out mouth with water, provided person is conscious. Seek medical advice.
   Inhalation
Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention.
   Skin
Immediately wash skin with soap and copious amounts of water for at least 15 minutes. If irritation persists, seek medical attention.
   Eyes
Immediately flush eyes with copious amounts of water for at least 15 minutes. Seek medical advice.

Transport.