4-(1,1,3,3-Tetramethylbutyl)phenol

  • p-Octylphenol
  • p-tert-Octylphenol
  • 4-tert-Octylphenol
  • p-(1',1',3',3'-Tetramethylbutyl)fenol
  • p-(1,1,3,3-Tetramethylbutyl)phenol
Formula
4-[(CH3)2CCH2C(CH3)2]C6H4OH
Structure
Description
White solid.
Uses
Chemical intermediate for ethoxylated & phosphated anionic surfactants.

Registry Numbers and Inventories.
CAS
140-66-9
EC (EINECS/ELINCS)
205-426-2
RTECS
SM9625000
RTECS class
Tumorigen; Reproductive Effector; Primary Irritant
UN (DOT)
2430
Beilstein/Gmelin
513992
Beilstein Reference
4-06-00-03484
Swiss Giftliste 1
G-7716
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C14H22O
Formula mass
206.33
Melting point, °C
80 - 81
Boiling point, °C
279 - 281
Vapor pressure, mmHg
0.002 (25 C)
Density
0.932 g/cm3 (20 C)
Solubility in water
Insoluble
Refractive index
1.5135 (20 C)
pKa/pKb
10.15 (pKa)
Partition coefficient, pKow
4.93
Heat of fusion
20.4 kJ/mol
Heat of vaporization
54.2 kJ/mol
Heat of combustion
-8278 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
ELIMINATE all ignition sources. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Disposal code
3
Stability
No data.

Fire.
Flash Point,°C
147
Autoignition, °C
410
Upper exp. limit, %
5
Lower exp. limit, %
0.6
Fire fighting
Small Fires: Dry chemical, carbon dioxide or water spray. Large Fires: Dry chemical, carbon dioxide, alcohol-resistant foam or water spray.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
3
Exposure effects
   Ingestion
Nausea, vomiting and diarrhea are possible if ingested.
   Inhalation
Cough, tachypnea, and wheezing are common after inhalation.
   Skin
Redness, swelling and pain may occur.
   Eyes
See Inhalation.

First aid
 
   Ingestion
Emesis is not indicated due to the irritant nature of these agents. Charcoal - not recommended; it may promote vomiting and make endoscopic evaluation difficult. Dilution: immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 4 ounces/120 ml in a child). Neutralization - neutralization is not indicated. Although these agents are irritants, and therefore should not produce tissue damage, it is almost impossible to assure that a particular substance under a particular set of circumstances would not cause damage. Therefore, each patient should be examined with the idea that mucous membrane damage might have occurred.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove and isolate contaminated clothing and shoes. Immediately flush with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. If in a medical facility, sterile saline should be used to irrigate the eyes until the cul de sac is returned to neutrality. Some alkali exposures may require prolonged irrigation.

Transport.
UN number
2430
Response guide
Hazard class
8
Packing Group
I; II; III
 
21. Phenols. Cresols
HS Code
2907 13 00