4-Acetylanisole

  • 4'-Methoxyacetophenone
  • 1-(4-Methoxyphenyl)ethanone
  • 1-Acetyl-4-methoxybenzene
  • 4-Methoxyphenyl methyl ketone
  • Vananote
  • Linarodin
Formula
4-(CH3O)C6H4COCH3
Structure
Description
White to pale yellow solid. Pleasant odor.

Registry Numbers and Inventories.
CAS
100-06-1
EC (EINECS/ELINCS)
202-815-9
EC Class
harmful
R 22 36/38
RTECS
AM9240000
RTECS class
Human Data; Primary Irritant
Beilstein/Gmelin
742313
Beilstein Reference
4-08-00-00340
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C9H10O2
Formula mass
150.18
Melting point, °C
36 - 38
Boiling point, °C
152
Vapor pressure, mmHg
0.0005 (3 C)
Density
1.14 g/cm3 (20 C)
Solubility in water
Slightly soluble
Viscosity
0.47 cp (184 C)
Surface tension
25.1 g/s2 (184 C)
Refractive index
1.547 (41 C)

Hazards and Protection.
Storage
Do not store in direct sunlight. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Disposal code
3
Stability
Stable at room temperature in closed containers under normal storage and handling conditions. May discolor on exposure to light.
Incompatibilities
Strong oxidizng agents, strong bases.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
138
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam. Use agent most appropriate to extinguish fire.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Human systemic effects by inhalation include: a pulse rate increase without a fall in blood pressure and blood pressure elevation.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin
Get medical aid if irritation develops or persists. Wash clothing before reuse. Flush skin with plenty of soap and water.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2914 50 00