4'-Aminoacetanilide

  • Paracetamin
  • 1-Amino-4-(acetylamino)benzene
  • 4-(Acetylamino)aniline
  • Fourrine A
  • Oxidation Base 19
  • C.I. 76005
Formula
C8H10N2O
Structure
Description
White or slightly reddish solid.
Uses
Intermediate in the manufacture of azo dyes, pharmaceuticals.

Registry Numbers and Inventories.
CAS
122-80-5
EC (EINECS/ELINCS)
204-576-6
EC Class
irritant
R 36/38 42/43
S 22 26 36/37 45
RTECS
AD8225000
RTECS class
Mutagen; Primary Irritant
UN (DOT)
3335
Merck
13,410
Beilstein/Gmelin
742888
Beilstein Reference
4-13-00-00137
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H10N2O
Formula mass
150.18
Melting point, °C
165
Boiling point, °C
267
Vapor pressure, mmHg
0.01 (25 C)
Density
1.27 g/cm3
Solubility in water
Soluble
Refractive index
1.52
pKa/pKb
9.43 (pKb)
Partition coefficient, pKow
0.08
Heat of vaporization
50.6 kJ/mol

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Do not expose to air. Store under an inert atmosphere.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Handle under an inert atmosphere. Store protected from air.
Protection
Eyes: Wear chemical goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Provide ventilation. Place under an inert atmosphere.
Disposal code
3
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Air.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
195
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire.
Fire potential
This material is probably combustible.

Health.
Exposure effects
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
3335
Response guide
HS Code
2924 29 95