4-Biphenylacetic acid

  • Napageln
  • p-Biphenylacetic acid
  • (1,1'-Biphenyl)-4-acetic acid
  • p-Biphenylylacetic acid
  • 4-Biphenylylacetic acid
  • 4-Carboxymethylbiphenyl
Formula
C14H12O2
Structure
Description
Beige powder.

Registry Numbers and Inventories.
CAS
5728-52-9
EC (EINECS/ELINCS)
227-233-2
EC Class
toxic
R 22 36/37/38
S 26 36/37/39
RTECS
DU8229050
RTECS class
Drug; Reproductive Effector
UN (DOT)
2811
Merck
13,3979
Beilstein/Gmelin
1211592
Beilstein Reference
4-09-00-02520
New Zealand
Listed

Properties.
Formula
C14H12O2
Formula mass
212.25
Melting point, °C
160 - 163
Boiling point, °C
365
Solubility in water
Soluble
pKa/pKb
4.29 (pKa)
Partition coefficient, pKow
3.21

Hazards and Protection.
Storage
Store in a cool, dry place. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Do not ingest or inhale. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Disposal code
4
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents, reducing agents, bases.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing media: Use agent most appropriate to extinguish fire. For small fires, use dry chemical, carbon dioxide, water spray or regular foam. For large fires, use water spray, fog or regular foam.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Animal studies have reported that fetal effects/abnormalities may occur when maternal toxicity is seen. Effects may be delayed.
   Ingestion
Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
Causes respiratory tract irritation.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2811
Response guide
HS Code
2916 39 00