4-Chloro-2-methylthiopyrimidine

  • 2-(Methylthio)-4-chloropyrimidine
  • 4-Chloro-2-(methylsulfanyl)pyrimidine
  • 4-Chloro-2-(methylmercapto)pyrimidine
Formula
C5H5ClN2S
Structure
Description
Clear dark brown.

Registry Numbers and Inventories.
CAS
49844-90-8
EC (EINECS/ELINCS)
256-500-6
R 36/38
UN (DOT)
1760
Beilstein/Gmelin
118042
Beilstein Reference
5-23-11-00113

Properties.
Formula
C5H5ClN2S
Formula mass
160.62
Boiling point, °C
243
Vapor pressure, mmHg
0.05 (25 C)
Density
1.381 g/cm3
Solubility in water
Slightly soluble
Refractive index
1.60 (20 C)
Partition coefficient, pKow
1.81
Heat of vaporization
46.1 kJ/mol

Hazards and Protection.
Storage
Corrosives area.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Eyes: Wear safety glasses and chemical goggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
101
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Not available.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
   Ingestion
Not available.
   Inhalation
May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Causes chemical burns to the respiratory tract.
   Skin
May cause severe irritation and possible burns.
   Eyes
Contact with eyes may cause severe irritation, and possible eye burns.

First aid
 
   Ingestion
Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.

Transport.
UN number
1760
Response guide
Hazard class
8
Packing Group
I; II; III