4-Chloro-3,5-dimethylphenol

  • Chloroxylenol
  • 4-Chloro-3,5-xylenol
Formula
4-(Cl)-3,5-(CH3)2C6H2OH
Structure
Description
White to cream colored crystals.
Uses
Antiseptic and germicide.

Registry Numbers and Inventories.
CAS
88-04-0
EC (EINECS/ELINCS)
201-793-8
EC Index Number
604-038-00-4
EC Class
Harmful; Irritant; Sensitising
R 22 36/38 43
RTECS
ZE6850000
RTECS class
Mutagen; Reproductive Effector; Human Data; Primary Irritant
UN (DOT)
3335
Merck
13,2194
Beilstein/Gmelin
1862539
Beilstein Reference
4-06-00-03152
EPA OPP
86801
Swiss Giftliste 1
G-3263
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H9ClO
Formula mass
156.61
Melting point, °C
114 - 116
Boiling point, °C
246
Vapor pressure, mmHg
0.02 (25 C)
Density
1.364 g/cm3
Solubility in water
0.3 g/L
pKa/pKb
9.76 (pKa)
Partition coefficient, pKow
3.35
Heat of vaporization
50.3 kJ/mol

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Disposal code
3
Stability
Stable at room temperature in closed containers under normal storage and handling conditions. Volatile in steam.
Incompatibilities
Strong oxidizing agents, strong bases.
Decomposition
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
132
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Health
1
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
3
Exposure effects
Animal studies have reported that fetal effects/abnormalities may occur when maternal toxicity is seen. Laboratory experiments have resulted in mutagenic effects.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
Causes irritation of the mucous membrane and upper respiratory tract.
   Skin
Causes skin irritation. May cause an allergic reaction in certain individuals.
   Eyes
Causes moderate eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
3335
Response guide
HS Code
2908 10 00