4-Chloro-o-toluidine

  • 4-Chloro-2-methylaniline
  • 4-Chloro-2-methylbenzenamine
  • para-Chloro-ortho-toluidine
  • 2-Amino-5-chlorotoluene
Formula
C7H8ClN
Structure
Description
Leaflets.
Uses
Chemical intermediate for ci azoic coupling component 8, ci pigment red 7, azoic diazo component for cotton, silk, acetate & nylon.

Registry Numbers and Inventories.
CAS
95-69-2
EC (EINECS/ELINCS)
202-441-6
EC Index Number
612-196-00-0
RTECS
XU5000000
RTECS class
Tumorigen; Mutagen
UN (DOT)
2239
Beilstein/Gmelin
878505
Beilstein Reference
4-12-00-01796
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C7H8ClN
Formula mass
141.61
Melting point, °C
27.2
Boiling point, °C
241
Vapor density (air=1)
4.9
Critical temperature
471
Critical pressure
40.1
Density
1.14 g/cm3 (20 C)
pKa/pKb
10.15 (pKb)
Partition coefficient, pKow
2.28

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Wash hands before eating. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Acids, acid chlorides, acid anhydrides, chloroformates, strong oxidizing agents, copper chloride.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
99
Autoignition, °C
560
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam. Use agent most appropriate to extinguish fire.
Fire potential
This material is combustible.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Toxic oxides of nitrogen and hydrochloric acid fumes may form.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Carcinogin
I-2A, N-2, CP65
Exposure effects
May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis, rapid heart rate, unconsciousness and possible death. May cause cancer in humans.
   Ingestion
May cause irritation of the digestive tract. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood.
   Inhalation
May cause respiratory tract irritation. May cause methemoglobinemia, cyanosis, convulsions, tachycardia, dyspnea, and death. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown blood. Inhalation of aniline causes anoxia due to the formation of methemoglobinemia.
   Skin
May cause skin irritation. If absorbed, causes symptoms similar to inhalation.
   Eyes
Dust may cause mechanical irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2239
Response guide
Hazard class
6.1
Packing Group
III
 
USCG CHRIS Code
CTD