4-Chlorobenzeneacetic acid

  • Benzeneacetic acid, 4-chloro-
  • (4-Chlorophenyl)acetic acid
  • (p-Chlorophenyl)acetic acid
  • 2-(p-Chlorophenyl)acetic acid
  • PCPA
Formula
4-(Cl)C6H4CH2COOH
Structure
Description
White to cream solid.

Registry Numbers and Inventories.
CAS
1878-66-6
EC (EINECS/ELINCS)
217-521-6
EC Class
irritant
R 36/37/38
RTECS
AG0590000
RTECS class
Drug
Beilstein/Gmelin
1072816
Beilstein Reference
4-09-00-01675
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C8H7ClO2
Formula mass
170.60
Melting point, °C
101 - 104
Boiling point, °C
292
Density
1.43 g/cm3
Solubility in water
Very soluble
pKa/pKb
4.17 (pKa)
Partition coefficient, pKow
2.09

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal.
Stability
No data.
Incompatibilities
Strong bases, strong oxidizing agents.
Decomposition
Hydrogen chloride, carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use agent most appropriate to extinguish fire.

Health.
Exposure effects
   Ingestion
The toxicological properties of this substance have not been fully investigated.
   Inhalation
The toxicological properties of this substance have not been fully investigated.
   Skin
The toxicological properties of this material have not been fully investigated.
   Eyes
No information regarding eye irritation and other potential effects was found.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
HS Code
2916 39 00