4-Chlorophenoxyacetic acid

  • p-Chlorophenoxyacetic acid
  • Acetic acid, (p-chlorophenoxy)
  • Parachlorophenoxyacetic acid
Formula
C8H7ClO3
Structure
Description
Prisms or needles from water.
Uses
Plant growth regulator.

Registry Numbers and Inventories.
CAS
122-88-3
EC (EINECS/ELINCS)
204-581-3
EC Index Number
607-073-00-3
EC Class
Harmful
RTECS
AG0175000
RTECS class
Agricultural Chemical and Pesticide; Drug; Mutagen
UN (DOT)
2811
Beilstein/Gmelin
1211804
Beilstein Reference
4-06-00-00845
EPA OPP
19401
Swiss Giftliste 1
G-1547
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H7ClO3
Formula mass
186.59
Melting point, °C
160
Boiling point, °C
308
Critical temperature
523
Critical pressure
36.9
Density
1.53 g/cm3
Solubility in water
Slightly soluble.
pKa/pKb
3.56 (pKa)
Partition coefficient, pKow
1.73

Hazards and Protection.
Storage
Keep containers tightly closed. Store in a cool, dry area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Do not ingest or inhale. Use with adequate ventilation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, strong bases.
Decomposition
Hydrogen chloride, carbon monoxide, carbon dioxide, chloride fumes.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
Low dose exposures - vertigo, headache, malaise, and paresthesias may occur depending on the specific compound involved. High dose exposures - muscle twitching, spasms, profound weakness, polyneuritis, and unconsciousness may occur depending on the specific compound involved. Idiosyncratic reactions - peripheral neuropathies 2,4-D and 2,4,5-T have caused adverse reproductive effects in experimental animals. Allegations of human birth defects due to these compounds have not been confirmed.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.
   Inhalation
May cause respiratory tract irritation. May cause irritation of the mucous membranes.
   Skin
May cause skin irritation. Individuals with pre-existing skin orders may be more susceptible to the effects of this substance.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Get medical aid immediately. Vomiting may occur spontaneously. If vomiting occurs and the victim is conscious, give water to further dilute the chemical.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2811
Response guide
HS Code
2918 90 90