4-Chlorotoluene

  • 1-Chloro-4-methylbenzene
  • 4-Chloro-1-methyl-benzene
  • p-Tolyl chloride
Formula
C7H7Cl
Structure
Description
Colorless liquid, characteristic, aromatic odor.
Uses
Solvent & intermediate for organic chemicals & dyes.

Registry Numbers and Inventories.
CAS
106-43-4
EC (EINECS/ELINCS)
203-397-0
EC Index Number
602-040-00-X
EC Class
Harmful; Dangerous for the Environment
R 20 51/53
S 24/25 61
RTECS
XS9010000
RTECS class
Mutagen
UN (DOT)
2238
Merck
13,2190
Beilstein/Gmelin
1903635
Beilstein Reference
4-05-00-00806
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H7Cl
Formula mass
126.59
Melting point, °C
6 - 8
Boiling point, °C
162
Vapor pressure, mmHg
3.4 (25 C)
Vapor density (air=1)
4.37
Saturation Concentration
0.34% (20 C) (calculated)
Critical temperature
385.7
Density
1.070 g/cm3 (20 C)
Solubility in water
<0.1 g/100 mL
Viscosity
1.033 cp (10 C)
Surface tension
32.9 g/s2 (25 C)
Refractive index
1.5250 (25 C)
Partition coefficient, pKow
3.33
Heat of vaporization
38.8 kJ/mol
Heat of combustion
-3754 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with skin and eyes. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Use with adequate ventilation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.
Disposal code
2
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Hydrogen chloride, chlorine, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
51
Autoignition, °C
595
Upper exp. limit, %
12.2
Lower exp. limit, %
0.7
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential
Slight risk when exposed to heat or flame.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
3 (Strong toxins)
Exposure effects
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal.
   Inhalation
Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2238
Response guide
Hazard class
3
Packing Group
III
 
USCG CHRIS Code
CRN
 
36 Halogenated hydrocarbons
HS Code
2903 69 90
 
IMO Chemical Code
17
IMO Pollution Category
B
IMO Hazard code
S/P