4-Hydroxyphenoxyacetic acid

  • p-Hydroxyphenoxyacetic acid
  • (4-Hydroxyphenoxy)acetic acid
  • O-(4-Hydroxyphenyl)glycolic acid
Formula
C8H8O4
Structure
Description
Off-white to beige crystalline powder.

Registry Numbers and Inventories.
CAS
1878-84-8
EC (EINECS/ELINCS)
217-525-8
R 36/37/38
Beilstein/Gmelin
1952779
Beilstein Reference
4-06-00-05744
Canada DSL/NDSL
NDSL
US TSCA
Listed

Properties.
Formula
C8H8O4
Formula mass
168.14
Melting point, °C
152-156
Boiling point, °C
327
Solubility in water
Very soluble
pKa/pKb
3.27 (pKa)
Partition coefficient, pKow
0.78

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Avoid breathing dust, vapor, mist, or gas. Do not get on skin and clothing.
Protection
Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear a chemical apron.
Respirators
A NIOSH/MSHA approved air purifying dust or mist respirator or European Standard EN 149.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Health.
Exposure effects
   Ingestion
The toxicological properties of this substance have not been fully investigated.
   Inhalation
Causes respiratory tract irritation.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Get medical aid. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.

Transport.