4-Iodoaniline

  • 4-Iodobenzenamine
  • 1-Iodo-4-aminobenzene
  • p-Aminoiodobenzene
  • 4-Iodophenylamine
Formula
4-(I)C6H4NH2
Structure
Description
Gray powder.

Registry Numbers and Inventories.
CAS
540-37-4
EC (EINECS/ELINCS)
208-743-4
EC Class
harmful
R 20/21/22
S 22 36/37
RTECS
BY3850000
RTECS class
Mutagen
UN (DOT)
2811
Merck
13,5049
Beilstein/Gmelin
774101
Beilstein Reference
4-12-00-01544
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C6H6IN
Formula mass
219.03
Melting point, °C
61 - 64
Boiling point, °C
262
Vapor density (air=1)
7.55
Critical temperature
534
Critical pressure
47.4
Solubility in water
Slightly soluble
pKa/pKb
10.19 (pKb)
Partition coefficient, pKow
2.32

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from light.
Handling
Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Do not get on skin and clothing. Keep container tightly closed. Do not ingest or inhale. Use with adequate ventilation. Store protected from light.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Disposal code
9
Stability
Stable at room temperature in closed containers under normal storage and handling conditions. May discolor on exposure to light.
Incompatibilities
Keep away from acids, acid chlorides, acetic anhydride, strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen, hydrogen iodide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Effects may be delayed.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed. May form methemoglobin which in sufficient concentration causes cyanosis.
   Inhalation
Causes respiratory tract irritation. Can produce delayed pulmonary edema.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation. May cause chemical conjunctivitis.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth respiration if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2811
Response guide
HS Code
2921 42 10