4-Methyl-2,6-dinitrophenol

  • Dinitro-p-cresol
  • 2,6-Dinitro-p-cresol
  • 2,6-Dinitro-4-methylphenol
  • Dnpc
  • Victoria orange
Formula
C7H6N2O5
Structure
Description
Yellow-orange flakes.
Uses
Parent compd for intermediates, dyes and pharmaceuticals.

Registry Numbers and Inventories.
CAS
609-93-8
EC (EINECS/ELINCS)
210-203-8
RTECS
GO9800000
RTECS class
Drug; Mutagen
UN (DOT)
2811
Beilstein/Gmelin
1978786
Beilstein Reference
4-06-00-02152
Canada DSL/NDSL
DSL
US TSCA
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H6N2O5
Formula mass
198.15
Melting point, °C
77-79
Solubility in water
insoluble
pKa/pKb
4.23 (pKa)
Partition coefficient, pKow
1.81

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
NIOSH approved respirator; goggles or face shield; protective clothing; rubber gloves.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks
Sweep up, then place into a suitable container for disposal.
Stability
Stable under normal temperatures and pressures. Appear to be stable in acid solution, but are susceptible to decomposition by UV radiation in alkaline solution.
Incompatibilities
Strong oxidizing agents, strong bases, acid chlorides, acid anhydrides.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Blood pressure, pulse, respiratory rate, and temperature may all be elevated after exposure. In severe poisoning, restlessness, seizures, and coma may occur. Animal studies show developmental malformations involving the neurologic, ophthalmic, urologic, and skeletal systems of offsprings.
   Ingestion
Nausea, vomiting, and abdominal pain may be prominent.
   Inhalation
Dyspnea, tachypnea, cyanosis, and pulmonary edema may occur.
   Skin
Yellow staining of skin occurs following contact with nitrophenols. Diaphoresis is common.
   Eyes
Cataracts, secondary glaucoma, symblepharon, paresis of accomodation, and nystagmus have been reported.

First aid
 
   Ingestion
Remove from exposure to fresh air immediately.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Wash affected areas of skin and hair vigorously with soap and water. Dermal exposure is usually accompanied by a yellowish discoloration which does not have to be removed completely to prevent absorption.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
USCG CHRIS Code
DNC