4,4'-Methylenebis(2-chloroaniline)

  • 3,3'-Dichloro-4,4'-diaminodiphenylmethane
  • 4,4'-Methylenebis[o-chloroaniline]
  • 4,4'-Methylenebis(2-chlorobenzenamine)
Formula
C13H12Cl2N2
Structure
Description
Tan-colored pellets or an off-white solid. Slight odor.
Uses
In manufacture of gun mounts, jet engine turbine blades, radar systems, and components in home appliances.

Registry Numbers and Inventories.
CAS
101-14-4
EC (EINECS/ELINCS)
202-918-9
EC Index Number
612-078-00-9
EC Class
Carcinogenic Category 2; Harmful; Dangerous for the Environment
RTECS
CY1050000
RTECS class
Tumorigen; Mutagen
UN (DOT)
2018
Merck
12,6136
Beilstein/Gmelin
1882318
Beilstein Reference
1-13-00-00074
RCRA
U158
Swiss Giftliste 1
G-6438
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C13H12Cl2N2
Formula mass
267.16
Melting point, °C
110
Boiling point, °C
405
Vapor pressure, mmHg
0.00005
Critical temperature
631
Critical pressure
29.7
Density
1.44 g/cm3 (20 C)
Solubility in water
Slightly Soluble
Partition coefficient, pKow
3.94

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
When exposed to heat above 200 degrees, it undergoes an exothermic and self-sustaining decomposition reaction. In a closed container the pressure build-up can be rapid enough to cause an explosion.
Incompatibilities
Avoid contact with chemically-active metals (e.g., potassium, sodium, magnesium, zinc).

Fire.
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
Fire potential
This material is probably combustible.

Health.
Exposure limit(s)
NIOSH REL: Ca TWA 0.003 mg/m3 [skin] See Appendix A
Carcinogin
G-A2, I-2A, N-2, CP65
Poison_Class
1*
Exposure effects
CNS effects include headache, dizziness, altered mental status, confusion (lethargy progressing coma), seizures, syncope; occur secondary to CNS hypoxia, usually with levels > 20%.
   Ingestion
Nausea and vomiting may occur.
   Inhalation
Dyspnea and tachypnea may occur.
   Skin
Central cyanosis unresponsive to oxygen therapy is classic.

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
2018
Response guide
USCG CHRIS Code
MCI