4,4'-Methylenebis(N-methylaniline)

  • Bis(N-methylaniline)methane
  • Dimethyldiaminodiphenylmethane
  • N,N'-Dimethyl-p-methylenedianiline
  • N,N'-Dimethyl-4,4'-diaminodiphenylmethane
Formula
C15H18N2
Structure
Uses
Major uses include chemical intermediate.

Registry Numbers and Inventories.
CAS
1807-55-2
EC (EINECS/ELINCS)
217-309-3
RTECS
BY5275000
RTECS class
Tumorigen; Mutagen
Beilstein/Gmelin
2109030
Beilstein Reference
2-13-00-00111
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C15H18N2
Formula mass
226.35
Melting point, °C
56 - 57
Boiling point, °C
394
Vapor pressure, mmHg
2E-6 (25 C)
Solubility in water
Insoluble
pKa/pKb
9.21 (pKb)
Heat of vaporization
64.4 kJ/mol

Hazards and Protection.

Fire.
Flash Point,°C
246

Health.
Exposure effects
   Ingestion
Signs and symptoms include central cyanosis, headache lethargy, dizziness, fatigue, syncope, dyspnea, CNS depression, seizures, dysrhythmia and shock. Symptoms may be delayed several hours after exposure. Nausea and vomiting may occur.
   Inhalation
See ingestion.
   Skin
See ingestion.
   Eyes
See ingestion.

First aid
 
   Ingestion
Administer charcoal as a slurry (240 mL water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents, 25 to 50 g in children (1 to 12 years), and 1 g/kg in infants less than 1 year old. Consider gastric lavage after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Protect airway by placement in Trendelenburg and left lateral decubitus position or by endotracheal intubation. Control any seizures first.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids.
   Skin
Skin should be thoroughly washed with soap and water Contaminated clothing and shoes should be discarded. Seek medical attention. Administer 100 percent humidified supplemental oxygen with assisted ventilation as required. Treat for methemoglobinemia and sequelae. Signs and symptoms of methemoglobinemia may be delayed.
   Eyes
Irrigate exposed eyes with copious amounts of room temperature water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.