4,4-Methylenebis(N,N-dimethyl) benzenamine

  • p,p'-Tetramethyldiamindiphenylmethane
  • Tetrabase
  • 4,4'-Methylenebis(N,N-dimethylaniline)
  • N,N,N',N'-Tetramethyl-4,4'-methylenedianiline
  • 4,4'-Methylenebis(N,N-dimethylaniline)
Formula
C17H22N2
Structure
Description
Yellowish glistening leaflets or plates or tan crystals. Weak odor. Sublimes without decomposition.
Uses
Chemical intermediate for dyes: eg, basic yellow 2, basic orange 14, solvent yellow 34, chemical intermediate for its hydrochloride salt, reagent for lead.

Registry Numbers and Inventories.
CAS
101-61-1
EC (EINECS/ELINCS)
202-959-2
EC Index Number
612-201-00-6
EC Class
carcinogenic
RTECS
BY5250000
RTECS class
Tumorigen; Mutagen
UN (DOT)
3259
Merck
12,6264
Beilstein/Gmelin
479956
Beilstein Reference
4-13-00-00390
Swiss Giftliste 1
G-8825
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C17H22N2
Formula mass
254.38
Melting point, °C
85 - 88
Boiling point, °C
390
Vapor pressure, mmHg
3E-6 (25 C)
Vapor density (air=1)
8.77
Density
1.14 g/cm3 (20 C)
Solubility in water
Insoluble
pKa/pKb
7.96 (pKb)
Partition coefficient, pKow
4.43
Heat of vaporization
63.9 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Disposal code
3
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Acids - acid chlorides - acid anhydrides - oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
173
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
This chemical is combustible.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure limit(s)
OSHA: Possible Select carcinogen
Carcinogin
N-2, CP65
Poison_Class
4
Exposure effects
May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis, rapid heart rate, unconsciousness and possible death. Animal inhalation studies have reported the development of tumors. Effects may be delayed. Laboratory experiments have resulted in mutagenic effects.
   Ingestion
Overexposure may cause methemoglobinemia. Causes digestive tract irritation.
   Inhalation
Causes respiratory tract irritation.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
3259
Response guide
Hazard class
8
Packing Group
I; II; III
 
USCG CHRIS Code
MLB
 
HS Code
2921 59 90