5-Bromo-2-nitrobenzotrifluoride

  • Toluene, 5-bromo-a,a,a-trifluoro-2-nitro-
  • 4-Bromo-1-nitro-2-(trifluoromethyl)benzene
  • 1-Bromo-4-nitro-3-(trifluoromethyl)benzene
Formula
C7H3BrF3NO2
Structure
Description
Yellow liquid.

Registry Numbers and Inventories.
CAS
344-38-7
R 20/21/22 36/38
S 26 36/37/39
UN (DOT)
2810
Beilstein/Gmelin
2650701
Beilstein Reference
4-05-00-00862

Properties.
Formula
C7H3BrF3NO2
Formula mass
270.00
Melting point, °C
40 - 45
Boiling point, °C
95 - 100 (5 torr)
Vapor density (air=1)
9.31
Density
1.799 g/cm3 (25 C)
Solubility in water
Insoluble
Refractive index
1.52 (20 C)

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Strong oxidizing agents, strong bases.
Decomposition
Carbon monoxide, oxides of nitrogen, carbon dioxide, hydrogen fluoride, hydrogen bromide.

Fire.
Flash Point,°C
>110
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Health.
Exposure effects
Effects may be delayed. Chronic ingestion may cause bromism characterized by disturbances of the central nervous system, skin and digestive tract. Chronic exposure to fluoride compounds may cause systemic toxicity.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Exposure to fluoride compounds can result in systemic toxic effects on the heart, liver, and kidneys. It may also deplete calcium levels in the body leading to hypocalcemia and death.
   Inhalation
Causes respiratory tract irritation. Inhalation of bromides may cause irritation of the upper respiratory tract and lung tissue. Can produce delayed pulmonary edema.
   Skin
Causes skin irritation. Exposure to bromides may cause rashes, especially of the face (resembling acne) and boils.
   Eyes
Causes eye irritation. May cause chemical conjunctivitis.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2810
Response guide