5-Iodo-2'-deoxyuridine

  • (+)-5-Iodo-2'-deoxyuridine
Formula
C9H11IN2O5
Structure
Description
White powder.

Registry Numbers and Inventories.
CAS
54-42-2
EC (EINECS/ELINCS)
200-207-8
RTECS
YU7700000
RTECS class
Tumorigen; Drug; Mutagen; Reproductive Effector
Merck
12,4934
Beilstein/Gmelin
30397
Beilstein Reference
4-24-00-01235
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C9H11IN2O5
Formula mass
354.1
Melting point, °C
164 - 166
Boiling point, °C
531
Solubility in water
2.0 mg/ml
Partition coefficient, pKow
-0.63

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Protection
Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen iodide.

Fire.
Autoignition, °C
350
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Health.
Exposure effects
   Ingestion
Harmful if swallowed. May cause irritation of the digestive tract.
   Inhalation
Harmful if inhaled. May cause respiratory tract irritation. Causes irritation of mucous membrane.
   Skin
May cause skin irritation. Harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Get medical aid. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.