5-Nitro-o-anisidine

  • 2-Methoxy-5-nitroaniline
  • Scarlet base R
Formula
C7H8N2O3
Structure
Description
Orange-red needles or orange powder.
Uses
Chemical intermediate for dyes and pigments (eg, ci pigment red 23), component in azoic dye compositions for cotton and nylon, acetate and silk.

Registry Numbers and Inventories.
CAS
99-59-2
EC (EINECS/ELINCS)
202-770-5
R 20/21/22 33 52
S 28 36/37 61
RTECS
BZ7175000
RTECS class
Tumorigen; Mutagen
UN (DOT)
2811
Beilstein/Gmelin
879620
Beilstein Reference
4-13-00-00896
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H8N2O3
Formula mass
168.17
Melting point, °C
118
Boiling point, °C
352
Vapor pressure, mmHg
4E-5 (25 C)
Density
1.2068 g/cm3 (156 C)
Solubility in water
Slightly soluble
pKa/pKb
11.58 (pKb)
Partition coefficient, pKow
1.47
Heat of vaporization
59.7 kJ/mol
Heat of combustion
-3666 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, acids, acid chlorides, acid anhydrides, chloroformates, liquid anisidine.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
167
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Combustible material; may burn but does not ignite readily. Extinguishing media: Water or foam may cause frothing. Use foam, dry chemical, or carbon dioxide.
Fire potential
This material is probably combustible.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
2
 
 
Reactivity
0
 

Health.
Exposure limit(s)
NIOSH: Potential Occupational Carcinogen.
Carcinogin
CP65
Exposure effects
May cause cancer according to animal studies.
   Ingestion
May cause irritation of the digestive tract.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
Dust may cause mechanical irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
USCG CHRIS Code
NAD