6-Bromo-a,a,a-trifluoro-m-toluidine

  • 2-Bromo-5-trifluoromethylaniline
  • 3-Amino-4-bromobenzotrifluoride
  • 4-Bromo-3-aminobenzotrifluoride
  • 2-Bromo-5-trifluoromethylphenylamine
  • Benzenamine, 2-bromo-5-(trifluoromethyl)-
Formula
C7H5BrF3N
Structure
Description
Yellow liquid.

Registry Numbers and Inventories.
CAS
454-79-5
EC (EINECS/ELINCS)
207-227-6
R 20/21/22 36/38
S 26 36/37/39
UN (DOT)
1760
Beilstein/Gmelin
2094535
Beilstein Reference
4-12-00-01857

Properties.
Formula
C7H5BrF3N
Formula mass
240.02
Melting point, °C
47-49
Boiling point, °C
94 - 96 (12 torr)
Vapor density (air=1)
8.28
Density
1.694 g/cm3 (25 C)
Solubility in water
Insoluble
Refractive index
1.52 (20 C)
pKa/pKb
1.31 (pKb)

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use with adequate ventilation. Discard contaminated shoes.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation.
Stability
No data.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, oxides of nitrogen, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride, hydrogen bromide.

Fire.
Flash Point,°C
> 110
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
   Ingestion
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. The toxicological properties of this substance have not been fully investigated.
   Inhalation
Causes chemical burns to the respiratory tract. The toxicological properties of this substance have not been fully investigated.
   Skin
Causes skin burns.
   Eyes
Causes eye burns.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid. Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
1760
Response guide
Hazard class
8
Packing Group
I; II; III