6-Chlorometanilic acid

  • p-Chloroaniline-m-sulfonic acid
  • 4-Chloroaniline-3-sulfonic acid
  • 3-Amino-6-chlorobenzenesulfonic acid
  • 5-Amino-2-chlorobenzenesulfonic acid
  • 1-Amino-4-chlorobenzene-3-sulfonic acid
Formula
C6H6ClNO3S
Structure
Description
White to light-grey powder.
Uses
Intermediate.

Registry Numbers and Inventories.
CAS
88-43-7
EC (EINECS/ELINCS)
201-830-8
Beilstein/Gmelin
2645353
Beilstein Reference
3-14-00-01915
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C6H6ClNO3S
Formula mass
207.64
Boiling point, °C
382
Solubility in water
Very soluble
pKa/pKb
3.27 (pKa)
Partition coefficient, pKow
0.95

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Follow the OSHA respirator regulations found in 29CFR 910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.
Stability
No data.
Incompatibilities
Strong oxidizing agents.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Exposure effects
The toxicological properties of this material have not been investigated.

First aid
 
   Ingestion
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Pesticides - remove contaminated clothing and jewelry. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing. Irritation - treat dermal irritation or burns with standard topical therapy
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.