7-Chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester

  • 7-Chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester
  • 7-Chloro-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester
Formula
C17H10ClF3N2O3
Structure

Registry Numbers and Inventories.
CAS
100491-29-0
Beilstein/Gmelin
4766094
Japan ENCS (MITI)
Listed

Properties.
Formula
C17H10ClF3N2O3
Formula mass
382.72
Melting point, °C
211 - 212
Solubility in water
Insoluble

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Protection
Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.
Stability
No data.
Incompatibilities
Strong oxidizing agents, acids, acetic anhydride, acid chlorides, carbon dioxide.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen fluoride.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use foam, dry chemical, or carbon dioxide.

Health.
Exposure effects
   Ingestion
May cause irritation of the digestive tract. May be harmful if swallowed. May cause difficulty in swallowing, stomach distension, possible cerebral swelling and
   Inhalation
Causes respiratory tract irritation. May be harmful if inhaled. May cause ulceration of nasal tissue, insomnia, nervous tremors with numb extremities, chemical pneumonia, shock, unconsciousness, and death.
   Skin
Causes skin irritation. May be harmful if absorbed through the skin. Exposure can produce pain, swelling, burns, and possible tissue destruction.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Get medical aid. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.