8-Hydroxyquinoline

  • Quinophenol
  • 8-Chinolinol
  • Oxybenzopyridine
  • Phenolpyridine
  • 8-Quinolinol
  • Oxichinolin
Formula
C9H7NO
Structure
Description
White to off-white or faintly yellow crystalline powder.
Uses
Microbiocide, Fungicide

Registry Numbers and Inventories.
CAS
148-24-3
EC (EINECS/ELINCS)
205-711-1
EC Class
harmful
R 20/21/22 40
S 22 36/37/39
RTECS
VC4200000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Drug; Mutagen; Primary Irritant
UN (DOT)
2811
Merck
13,4869
Beilstein/Gmelin
114512
Beilstein Reference
5-21-03-00252
EPA OPP
59803
Swiss Giftliste 1
G-2680
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C9H7NO
Formula mass
145.16
Melting point, °C
71.2
Boiling point, °C
267
Vapor pressure, mmHg
0.0051 (25 C)
Density
1.1594 g/cm3 (80 C)
Solubility in water
Soluble
Surface tension
39.68 g/s2 (99 C)
pKa/pKb
4.19 (pKb)
Partition coefficient, pKow
1.87
Heat of vaporization
52.5 kJ/mol
Heat of combustion
-4459 kJ/mol

Hazards and Protection.
Storage
Store in a cool place in the original container and protect from sunlight. Store protected from light.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Store protected from light. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Disposal code
3
Stability
Stable under normal temperatures and pressures. Darkens and decomposes on exposure to light.
Incompatibilities
Strong oxidizing agents, light, strong acids, common metals.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
131
Upper exp. limit, %
7
Lower exp. limit, %
1
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire.
Fire potential
This material is probably combustible.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
Possible cancer hazard based on tests with laboratory animals.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.
   Inhalation
Dust is irritating to the respiratory tract.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2811
Response guide
HS Code
2933 49 90