Acetaminophen

  • abensanil
  • acetagesic
  • p-Acetamidophenol
  • 4-Acetamidophenol
  • Acetaminofen
  • p-Acetaminophenol
Formula
CH3CONHC6H4(OH)
Structure
Description
Colorless crystals or crystalline powder, odorless.
Uses
Manufacture azo dyes.

Registry Numbers and Inventories.
CAS
103-90-2
EC (EINECS/ELINCS)
203-157-5
EC Class
harmful, dangerous for the environment
R 22 36/37/38
S 26 36/37/39
RTECS
AE4200000
RTECS class
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
Merck
13,48
Beilstein/Gmelin
2208089
Beilstein Reference
4-13-00-01091
EPA OPP
109509
Swiss Giftliste 1
G-1038
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H9NO2
Formula mass
151.17
Melting point, °C
168
Boiling point, °C
388
Vapor pressure, mmHg
1E-6 (25 C)
Density
1.34 g/cm3
Solubility in water
Insoluble
pKa/pKb
9.86 (pKa)
Partition coefficient, pKow
0.82
Heat of fusion
27.1 kJ/mol
Heat of vaporization
66.2 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Keep container closed when not in use.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
188
Autoignition, °C
540
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential
This material is probably combustible.

Health.
Poison_Class
3
Exposure effects
May cause cancer in humans.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Human systemic effects by ingestion: changes in exocrine pancreas, diarrhea, nausea, irritability, somnolence, general anesthesia, fever, hepatitis, kidney tubule damage.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
HS Code
2924 29 30